Evidence map›Paper›PMID 24374383›Full record

ReviewNeuroscience and biobehavioral reviews2014

Psychological processing in chronic pain: a neural systems approach.

Laura E Simons, Igor Elman, David Borsook

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03933189 (Physical Therapy for Individuals With Chronic Pain Due to Physical and/or Emotional Trauma), which is not on this map. Cited by 173 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 9 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03933189 nacompletednot on this mapstarted 2019, after this paper: background citation

Physical Therapy for Individuals With Chronic Pain Due to Physical and/or Emotional Trauma: A Comparison of Physical Therapy Interventions

TypeinterventionalSponsorUniversity of VermontRan2019 to 2021Enrolled98ConditionsChronic Pain, Disability PhysicalArmsPhysical Therapy
3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 9 syntheses or guidelines pooled it, 348 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of neuromodulation and rehabilitation approaches on pain relief in patients with spinal cord injury: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  13. Pain characteristics and nicotine deprivation as predictors of performance during a laboratory paradigm of smoking cessation.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
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113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Laura E SimonsCenter for Pain and the Brain, P.A.I.N. Group, Boston Children's Hospital, United States; Department of Psychiatry, United States; Harvard Medical School, United States. Electronic address: Laura.Simons@childrens.harvard.edu.
Igor ElmanVeterans Administration, United States.
David BorsookCenter for Pain and the Brain, P.A.I.N. Group, Boston Children's Hospital, United States; Harvard Medical School, United States.
Boston Children's Hospital · USCenter for Pain and the Brain · USUnited States Department of Veterans Affairs · US

Funding

Imaging Pain and Analgesia: Mentoring in Basic and Applied ResearchK24NS064050 · NINDS · MCLEAN HOSPITAL · PI BORSOOK, DAVID · 2008 to 2017
$1.7M
A neuroimaging perspective of pain-related fear in children with chronic painK23HD067202 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SIMONS, LAURA E · 2011 to 2015
$581k
NICHD NIH HHS HD067202NICHD NIH HHS K23 HD067202NINDS NIH HHS K24 NS064050NINDS NIH HHS NS064050
6 · The paper itself

Abstract

Our understanding of chronic pain involves complex brain circuits that include sensory, emotional, cognitive and interoceptive processing. The feed-forward interactions between physical (e.g., trauma) and emotional pain and the consequences of altered psychological status on the expression of pain have made the evaluation and treatment of chronic pain a challenge in the clinic. By understanding the neural circuits involved in psychological processes, a mechanistic approach to the implementation of psychology-based treatments may be better understood. In this review we evaluate some of the principle processes that may be altered as a consequence of chronic pain in the context of localized and integrated neural networks. These changes are ongoing, vary in their magnitude, and their hierarchical manifestations, and may be temporally and sequentially altered by treatments, and all contribute to an overall pain phenotype. Furthermore, we link altered psychological processes to specific evidence-based treatments to put forth a model of pain neuroscience psychology.

Indexed as

BrainChronic PainFemaleHumansMaleNerve NetSex FactorsAllostatic loadAmygdalaAnhedoniaAnterior cingulate cortexAnxietyAttentionBehaviorBrainCatastrophizingChronic painCognitionDepressionFearHippocampusImagingInsulaInteroceptionMotivationNeurocircuitNociceptionParietal cortexPerceptionPrefrontal cortexPsychologyReward

Identifiers

PMID24374383
PMCPMC3944001
OpenAlexW2065687898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.