ArticleAmerican journal of obstetrics and gynecology2014
Implications of sleep-disordered breathing in pregnancy.
Article in American journal of obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Fetal and neonatal outcomes of pregnancies complicated by maternal sleep-disordered breathing: a systematic review.Frontiers in physiology · 2026Pooled it
- Maternal sleep disordered breathing and offspring growth outcome: A systematic review and meta-analysis.Sleep medicine reviews · 2024Pooled it
- Influence of Obstructive Sleep Apnea on Maternal and Perinatal Outcomes in Patients With Gestational Diabetes Mellitus.Journal of sleep research · 2026Article
- Preliminary Evidence Linking Maternal Sleep-Disordered Breathing During Pregnancy to Early Childhood Development: A 3-Year Pilot Cohort Study in Japan.Children (Basel, Switzerland) · 2025Article
- Association of maternal nocturnal heart rate and adverse pregnancy outcomes.Pregnancy (Hoboken, N.J.) · 2025Article
- Home monitoring for clinically suspected obstructive sleep apnea in pregnancy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- A Relation between Obstructive Sleep Apnea in Pregnancy and Delivering Small for Gestational Age Infant-A Systematic Review.Journal of clinical medicine · 2023Review
- A Review of the Associations Between Obstructive Sleep Apnea and Gestational Diabetes Mellitus and Possible Mechanisms of Disease.Reproductive sciences (Thousand Oaks, Calif.) · 2023Review
- Common sleep disorders in pregnancy: a review.Frontiers in medicine · 2023Review
- Obstructive sleep apnea in pregnant women.International anesthesiology clinics · 2022Article
- On the Relationship between Diabetes and Obstructive Sleep Apnea: Evolution and Epigenetics.Biomedicines · 2022Review
- The association between obstructive sleep apnea and the risk of poor delivery events in women: A population-based nested case-control study.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2022Article
- Objectively assessed sleep-disordered breathing during pregnancy and infant birthweight.Sleep medicine · 2021Observational
- Sleep-disordered breathing in pregnancy: a developmental origin of offspring obesity?Journal of developmental origins of health and disease · 2021Review
- Influence of Obstructive Sleep Apnea on Systemic Inflammation in Pregnancy.Frontiers in medicine · 2021Article
- Article
- Sleep in Pregnancy and Maternal Hyperglycemia: a Narrative Review.Current diabetes reports · 2019Review
- Obstructive Sleep Apnea Is Associated With Altered Glycemic Patterns in Pregnant Women With Obesity.The Journal of clinical endocrinology and metabolism · 2019Article
- A review of the associations between obstructive sleep apnea and hypertensive disorders of pregnancy and possible mechanisms of disease.Sleep medicine reviews · 2018Review
- Obstructive Sleep Apnea in Pregnant Women: A Review of Pregnancy Outcomes and an Approach to Management.Anesthesia and analgesia · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe objective of the study was to examine the relationship between sleep-disordered breathing (SDB) and adverse pregnancy outcomes in a high-risk cohort. STUDY
designThis was a planned analysis of a prospective cohort designed to estimate the prevalence and trends of SDB in high-risk pregnant women. We recruited women with a body mass index of 30 kg/m(2) or greater, chronic hypertension, pregestational diabetes, prior preeclampsia, and/or a twin gestation. Objective assessment of SDB was completed between 6 and 20 weeks and again in the third trimester. SDB was defined as an apnea hypopnea index of 5 or greater and further grouped into severity categories: mild SDB (5-14.9), moderate SDB (15-29.9), and severe SDB (≥30). Pregnancy outcomes (preeclampsia, gestational diabetes, preterm birth, infant weight) were abstracted by physicians blinded to the SDB results.
resultsOf the 188 women with a valid early pregnancy sleep study, 182 had complete delivery records. There was no relationship demonstrated between SDB exposure in early or late pregnancy and preeclampsia, preterm birth less than 34 weeks, and small-for-gestational-age (<5%), or large-for-gestational-age (>95%) neonates. Conversely, SDB severity in early pregnancy was associated with the risk of developing gestational diabetes (no SDB, 25%; mild SDB, 43%; moderate/severe SDB, 63%; P = .03). The adjusted odds ratio for developing gestational diabetes for moderate/severe SDB was 3.6 (0.6, 21.8).
conclusionThis study suggests a dose-dependent relationship between SDB in early pregnancy and the subsequent development of gestational diabetes. In contrast, no relationships between SDB during pregnancy and preeclampsia, preterm birth, and extremes of birthweight were demonstrated.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.