ArticleJournal of clinical hypertension (Greenwich, Conn.)2014
The age-related hemodynamic changes of blood pressure and their impact on the incidence of cardiovascular disease and stroke: new evidence.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Predictive variables and diagnostic performance of cross-sectional models for hypertension detection: a systematic review.Frontiers in cardiovascular medicine · 2025Pooled it
- Trial
- Prediction of blood pressure changes during surgical incision using the minimum evoked current of vascular stiffness value under sevoflurane anesthesia.Scientific reports · 2023Trial
- Isolated Diastolic Hypertension and Cardiovascular Disease Risk in Young Adults.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Modulatory Effects of Hypertension on Aging-Related White Matter Hyperintensities: A Comparative Study Among Stroke Patients and Stroke-Free Community-Based Cohort.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- A Retrospective Study to Investigate the Relationship Between Body Mass Index and Hemodynamic Characteristics in Hypertensive Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2025Review
- Pulsatile microvascular cerebral blood flow waveforms change with intracranial compliance and age.Neurophotonics · 2024Article
- Short-Term L-Citrulline Supplementation Does Not Affect Blood Pressure, Pulse Wave Reflection, or Arterial Stiffness at Rest and during Isometric Exercise in Older Males.Sports (Basel, Switzerland) · 2023Article
- A flexible optoacoustic blood 'stethoscope' for noninvasive multiparametric cardiovascular monitoring.Nature communications · 2023Article
- Relationship of an adherence score with blood pressure control status among patients with hypertension and their determinants: Findings from a nationwide blood pressure screening program.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Time-efficient physical training for enhancing cardiovascular function in midlife and older adults: promise and current research gaps.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Review
- Vascular aging and subclinical atherosclerosis: why such a "never ending" and challenging story in cardiology?Clinical interventions in aging · 2017Review
- Gender, race, age, and regional differences in the association of pulse pressure with atrial fibrillation: the Reasons for Geographic and Racial Differences in Stroke study.Journal of the American Society of Hypertension : JASH · 2016Article
- Article
- Peripheral vascular disease is associated with increased pulse wave velocity and augmentation index: clinical implications.Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a linear change in blood pressure (BP) with the advancement of age from predominantly diastolic BP (DBP) in the young to predominantly systolic BP (SBP) in the old. This change is caused by the stiffening of the large arteries and the loss of elastic recoil as a result of replacement of the elastic fibers with collagen fibers. The result of this ageing process leads to an increase in pulse wave velocity and widening of pulse pressure. These hemodynamic changes are associated with an increased incidence in cardiovascular diseases (CVDs) and strokes. Recently, an inverse relationship with stroke risk was noted when the DBP was <71 mm Hg in persons older than 60 years. Accordingly, when treating SBP in the elderly, care should be taken not to lower the DBP below this level in order to minimize the risk for CVD and stoke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.