Evidence map›Paper›PMID 24373352›Full record

Trial reportThe Journal of allergy and clinical immunology2014

Plasminogen activator inhibitor-1 in sputum and nasal lavage fluids increases in asthmatic patients during common colds.

Seong H Cho, Seung J Hong, Haimei Chen, Ali Habib, David Cho, Sun H Lee, Joseph Kang, Theresa Ward, Homer A Boushey, Robert P Schleimer and 1 more

Open access · bronzeAbstract readClinical TrialLetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. PAI-1 gain-of-function genotype, factors increasing PAI-1 levels, and airway obstruction: The GALA II Cohort.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2017
    Article
  5. Article
  6. Therapeutic potential of an orally effective small molecule inhibitor of plasminogen activator inhibitor for asthma.American journal of physiology. Lung cellular and molecular physiology · 2016
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Seong H ChoDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill; Division of Rheumatology, Department of Medicine, Kyung Hee University School of Medicine, Seoul, Korea. Electronic address: seong-cho@northwestern.edu.
Seung J HongDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill; Division of Rheumatology, Department of Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Haimei ChenDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
Ali HabibDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
David ChoDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
Sun H LeeDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
Joseph KangDepartment of Preventive Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
Theresa WardDepartment of Medicine, Cardiovascular Research Institute, University of California at San Francisco, San Francisco, Calif.
Homer A BousheyDepartment of Medicine, Cardiovascular Research Institute, University of California at San Francisco, San Francisco, Calif.
Robert P SchleimerDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
Pedro C AvilaDivision of Allergy-Immunology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Ill.
Northwestern University · USUniversity of California, San Francisco · US

Funding

New Paradigms in Gene Regulation During Influenza Virus InfectionsU01AI082984 · NIAID · NORTHWESTERN UNIVERSITY · PI HORVATH, CURT M · 2009 to 2013
$3.6M
Glucocorticosteroid Action In Inflammatory DiseaseR37HL068546 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2009 to 2018
$3.5M
VIRUSES, EPITHELIUM CELLS AND AIRWAY FUNCTION IN ASTHMAP01AI050496 · NIAID · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI BOUSHEY, HOMER A · 2001 to 2004
$3.5M
Role of Epithelium in Immunity, Inflammation and DiseaseR01HL078860 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2006 to 2013
$3.0M
Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisP01AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2013 to 2013
$1.7M
Microarray-based detection and typing of rhinovirusesR21AI057506 · NIAID · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI BOUSHEY, HOMER A · 2004 to 2005
$436k
NHLBI NIH HHS R01 HL078860NHLBI NIH HHS R01-HL078860NHLBI NIH HHS R37 HL068546NHLBI NIH HHS R37-HL068546NIAID NIH HHS P01 AI050496NIAID NIH HHS P01-AI050496NIAID NIH HHS P01 AI106683NIAID NIH HHS R21 AI057506NIAID NIH HHS R21-AI057506NIAID NIH HHS U01 AI082984NIAID NIH HHS U01-AI082984
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAsthmaChildCommon ColdFemaleHumansMaleMiddle AgedPlasminogen Activator Inhibitor 1SputumPlasminogen Activator Inhibitor 1SERPINE1 protein, human

Identifiers

PMID24373352
PMCPMC4004714
OpenAlexW2162879802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.