SynthesisInfluenza and other respiratory viruses2014
Influenza outbreak control practices and the effectiveness of interventions in long-term care facilities: a systematic review.
Synthesis in Influenza and other respiratory viruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Systematic review of influenza vaccine effectiveness against laboratory-confirmed influenza among older adults living in aged care facilities.Human vaccines & immunotherapeutics · 2023Pooled it
- The use of masks to protect against respiratory infections: An umbrella review.Enfermedades infecciosas y microbiologia clinica (English ed.) · 2021Pooled it
- Pooled it
- The burden of respiratory infections among older adults in long-term care: a systematic review.BMC geriatrics · 2019Pooled it
- Trial
- Article
- Modeling the Impacts of Antiviral Prophylaxis Strategies in Mitigating Seasonal Influenza Outbreaks in Nursing Homes.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- AMMI Canada 2023 update on influenza: Management and emerging issues.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023Article
- Responses to infectious disease outbreaks in supported living environments for individuals with neurodevelopmental disorders: a scoping review.International journal of developmental disabilities · 2023Article
- Modeling scenarios for mitigating outbreaks in congregate settings.PLoS computational biology · 2022Article
- Nonpharmaceutical interventions to prevent viral respiratory infection in community settings: an umbrella review.ERJ open research · 2022Review
- Impact assessment of COVID-19 non-pharmaceutical interventions in long term care facilities in Cyprus: Safety improvement strategy.Safety science · 2021Article
- Mitigating outbreaks in congregate settings by decreasing the size of the susceptible population.medRxiv : the preprint server for health sciences · 2021Article
- Successful management of COVID-19 outbreak in a long-term care facility in Jeddah, Saudi Arabia: Epidemiology, challenges for prevention and adaptive management strategies.Journal of infection and public health · 2021Article
- Epidemiology of 2017 influenza outbreaks in nine Australian Aged care facilities.Influenza and other respiratory viruses · 2021Article
- Article
- The use of masks to protect against respiratory infections: an umbrella review.Enfermedades infecciosas y microbiologia clinica (English ed.) · 2020Article
- Antiviral Chemoprophylaxis Use During Influenza Outbreaks in Rhode Island Long-Term Care Facilities.Journal of the American Medical Directors Association · 2020Article
- Effectiveness of Oseltamivir Prophylaxis in Influenza Outbreaks in Residential Aged Care.Journal of epidemiology and global health · 2020Article
- Influenza A (H1N1): outbreak management in a dialysis unit and clinical outcomes of infection in chronic hemodialysis patients.Jornal brasileiro de nefrologia · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundEvaluation of influenza control measures frequently focuses on the efficacy of chemoprophylaxis and vaccination, while the effectiveness of non-pharmaceutical interventions (NPI) receives less emphasis. While influenza control measures are frequently reported for individual outbreaks, there have been few efforts to characterize the real-world effectiveness of these interventions across outbreaks.
objectivesTo characterize influenza case and outbreak definitions and control measures reported by long-term care facilities (LTCFs) of elderly adults and estimate the reduction in influenza-like illness (ILI) attack rates due to chemoprophylaxis and NPI.
methodsWe conducted a literature search in PubMed including English-language studies reporting influenza outbreaks among elderly individuals in LTCFs. A Bayesian hierarchical logistic regression model estimated the effects of control measures on ILI attack rates.
resultsOf 654 articles identified in the literature review, 37 articles describing 60 influenza outbreaks met the inclusion criteria. Individuals in facilities where chemoprophylaxis was used were significantly less likely to develop influenza A or B than those in facilities with no interventions [odds ratio (OR) 0·48, 95% CI: 0·28, 0·84]. Considered by drug class, adamantanes significantly reduced infection risk (OR 0·22, 95% CI: 0·12, 0·42), while neuraminidase inhibitors did not show a significant effect. Although NPI showed no significant effect, the results suggest that personal protective equipment may produce modest protective effects.
conclusionsOur results indicate pharmaceutical control measures have the clearest reported protective effect in LTCFs. Non-pharmaceutical approaches may be useful; however, most data were from observational studies and standardized reporting or well-conducted clinical trials of NPI are needed to more precisely measure these effects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.