Evidence map›Paper›PMID 24373291›Full record

ArticleInfluenza and other respiratory viruses2014

International flight-related transmission of pandemic influenza A(H1N1)pdm09: an historical cohort study of the first identified cases in the United Kingdom.

Nicholas Young, Richard Pebody, Gillian Smith, Babatunde Olowokure, Giri Shankar, Katja Hoschler, Monica Galiano, Helen Green, Anders Wallensten, Angela Hogan and 1 more

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Review
  7. Review
  8. Article
  9. A large national outbreak of COVID-19 linked to air travel, Ireland, summer 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
  10. Article
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  12. The Airplane Cabin Microbiome.Microbial ecology · 2019
    Article
  13. Review
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  15. Article
  16. Article
  17. Airport exit and entry screening for Ebola--August-November 10, 2014.MMWR. Morbidity and mortality weekly report · 2014
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicholas YoungHealth Protection Agency, Bristol, UK.
Richard Pebody
Gillian Smith
Babatunde Olowokure
Giri Shankar
Katja Hoschler
Monica Galiano
Helen Green
Anders Wallensten
Angela Hogan
Isabel Oliver

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransporting over two billion passengers per year, global airline travel has the potential to spread emerging infectious diseases, both via transportation of infectious cases and through in-flight transmission. Current World Health Organization (WHO) guidance recommends contact tracing of passengers seated within two rows of a case of influenza during air travel.

objectivesThe objectives of this study were to describe flight-related transmission of influenza A(H1N1)pdm09 during a commercial flight carrying the first cases reported in the United Kingdom and to test the specific hypothesis that passengers seated within two rows of an infectious case are at greater risk of infection.

methodsAn historical cohort study, supplemented by contact tracing, enhanced surveillance data and laboratory testing, was used to establish a case status for passengers on board the flight.

resultsData were available for 239 of 278 (86·0%) of passengers on the flight, of whom six were considered infectious in-flight and one immune. The attack rate (AR) was 10 of 232 (4·3%; 95% CI 1·7-6·9%). There was no evidence that the AR for those seated within two rows of an infectious case was different from those who were not (relative risk 0·9; 95% CI 0·2-3·1; P = 1·00). Laboratory testing using PCR and/or serology, available for 118 of 239 (49·4%) of the passengers, was largely consistent with clinically defined case status.

conclusionsThis study of A(H1N1)pdm09 does not support current WHO guidance regarding the contact tracing of passengers seated within two rows of an infectious case of influenza during air travel.

Indexed as

Air TravelCohort StudiesContact TracingFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMaleUnited KingdomAircraftinfluenzapandemicsprevention and controltransmissiontravel

Identifiers

PMID24373291
PMCPMC4177799

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.