ArticleTropical medicine & international health : TM & IH2014
Seasonal and gestation stage associated differences in aflatoxin exposure in pregnant Gambian women.
Article in Tropical medicine & international health : TM & IH, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Level of exposure to aflatoxins during pregnancy and its association with adverse birth outcomes in Africa: a meta-analysis.International health · 2024Pooled it
- Agricultural and nutritional education interventions for reducing aflatoxin exposure to improve infant and child growth in low- and middle-income countries.The Cochrane database of systematic reviews · 2020Pooled it
- Aflatoxins and Human Health: Global Exposure, Disease Burden, and One Health Strategies.Toxins · 2026Review
- A Cross-Sectional Association Between Serum Aflatoxin and Micronutrient Status Among Children Aged 6-24 Months in Rural Tanzania.Maternal & child nutrition · 2025Article
- Association between low maternal serum aflatoxin B1 exposure and adverse pregnancy outcomes in Mombasa, Kenya, 2017-2019: A nested matched case-control study.Maternal & child nutrition · 2024Article
- Dietary, socioeconomic, and maize handling practices associated with aflatoxin and fumonisin exposure among women tortilla makers in 5 departments in Guatemala.PLOS global public health · 2024Article
- The PRECISE-DYAD protocol: linking maternal and infant health trajectories in sub-Saharan Africa.Wellcome open research · 2022Article
- Effects of Prenatal Exposure to Aflatoxin B1: A Review.Molecules (Basel, Switzerland) · 2021Review
- Aflatoxin Exposure during Early Life Is Associated with Differential DNA Methylation in Two-Year-Old Gambian Children.International journal of molecular sciences · 2021Article
- Seasonal modulation of antibody response to diphtheria-tetanus-pertussis vaccination in infants: a cohort study in rural Gambia.BMC public health · 2021Article
- Impact of dietary aflatoxin on immune development in Gambian infants: a cohort study.BMJ open · 2021Article
- Aflatoxin exposure and child nutrition: measuring anthropometric and long-bone growth over time in Nepal.The American journal of clinical nutrition · 2021Article
- Human aflatoxin exposure in Uganda: Estimates from a subset of the 2011 Uganda AIDS indicator survey (UAIS).Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment · 2021Article
- Maternal aflatoxin exposure during pregnancy and adverse birth outcomes in Uganda.Maternal & child nutrition · 2019Article
- Environmental Health Research in Africa: Important Progress and Promising Opportunities.Frontiers in genetics · 2019Review
- Aflatoxin exposure assessed by aflatoxin albumin adduct biomarker in populations from six African countries: REVIEW ARTICLE.World mycotoxin journal · 2018Review
- Chronic aflatoxin exposure in children living in Bhaktapur, Nepal: Extension of the MAL-ED study.Journal of exposure science & environmental epidemiology · 2017Article
- Engaging One Health for Non-Communicable Diseases in Africa: Perspective for Mycotoxins.Frontiers in public health · 2017Review
- The large contribution of twins to neonatal and post-neonatal mortality in The Gambia, a 5-year prospective study.BMC pediatrics · 2016Article
- Dietary exposure to aflatoxin and micronutrient status among young children from Guinea.Molecular nutrition & food research · 2016Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveAflatoxin is known to cross the placental barrier and exposures in utero could influence genomic programming, foetal growth and development, resulting in long-term health effects. We aimed to determine aflatoxin exposure in Gambian women at two stages of pregnancy and during the rainy and dry seasons.
methodsWe examined aflatoxin exposure in pregnant Gambian women at early (<16 weeks) and later (16 weeks onward) stages of pregnancy and at different times of the year, during the rainy (June to October 2009) or dry (November to May 2010) season, using aflatoxin-albumin adducts (AF-alb).
resultsMean AF-alb was higher during the dry season than in the rainy season, in both early and later pregnancy although the difference was strongest in later pregnancy. There was a modest increase in AF-alb in later than early pregnancy (geometric mean 41.8 vs. 34.5 pg/mg, P < 0.05), but this was restricted to the dry season when exposures were generally higher.
conclusionsThe study confirmed that Gambian pregnant women were exposed to aflatoxin throughout the pregnancy, with higher levels in the dry season. There was some evidence in the dry season that women in later pregnancy had higher AF-alb levels than those in earlier pregnancy. Further research on the effects of exposure to this potent mutagen and carcinogen throughout pregnancy, including the epigenetic modification of foetal gene expression and impact on pre- and post-natal growth and development, are merited.
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