Evidence map›Paper›PMID 24372513›Full record

ReviewACS chemical biology2014

Small molecules for cell reprogramming and heart repair: progress and perspective.

Min Xie, Nan Cao, Sheng Ding

Abstract readReview
In one paragraph

Review in ACS chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Translational aspects of cardiac cell therapy.Journal of cellular and molecular medicine · 2015
    Review
  7. Article
  8. Generation of pluripotent stem cells without the use of genetic material.Laboratory investigation; a journal of technical methods and pathology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Min XieThe Gladstone Institutes, 1650 Owens Street, San Francisco, California 94158, United States.
Nan Cao
Sheng Ding

Funding

Generation of human iPS cells by chemically defined conditionsR01HD064610 · NICHD · SCRIPPS RESEARCH INSTITUTE, THE · PI DING, SHENG · 2010 to 2014
$1.9M
NICHD NIH HHS R01 HD064610
6 · The paper itself

Abstract

Regenerative medicine for heart failure seeks to replace lost cardiomyocytes. Chemical approaches for producing ample supplies of cells, such as pluripotent stem cells and cardiomyocytes, hold promise as practical means to achieve safe, facile cell-based therapy for cardiac repair and regenerative medicine. In this review, we describe recent advances in the application of small molecules to improve the generation and maintenance of pluripotent stem cells. We also describe new directions in heart repair and regeneration in which chemical approaches may find their application.

Indexed as

RegenerationAnimalsCell- and Tissue-Based TherapyHeartHeart FailureHumansMyocytes, CardiacPluripotent Stem CellsRegenerative MedicineSmall Molecule LibrariesSmall Molecule Libraries

Identifiers

PMID24372513
PMCPMC3951179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.