ArticleTransfusion2014
Predictors of iron levels in 14,737 Danish blood donors: results from the Danish Blood Donor Study.
Article in Transfusion, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04250298 (Pilot Study to Gain First Indications for the Impact of a Three-month's Oral Intake of an Iron Supplement With High Bioavailability on the Hemoglobin Concentration in Iron Deficient Blood Donors), which is not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study to Gain First Indications for the Impact of a Three-month's Oral Intake of an Iron Supplement With High Bioavailability on the Hemoglobin Concentration in Iron Deficient Blood Donors
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Diagnostic accuracy of reticulocyte haemoglobin content in detecting iron deficiency without anaemia in blood donors: A systematic review and meta-analysis.Vox sanguinis · 2026Pooled it
- Is Higher Consumption of Animal Flesh Foods Associated with Better Iron Status among Adults in Developed Countries? A Systematic Review.Nutrients · 2016Pooled it
- Consumption of Different Egg-Based Diets Alters Clinical Metabolic and Hematological Parameters in Young, Healthy Men and Women.Nutrients · 2023Trial
- Genetic factors associated with iron storage in Australian blood donors.Blood transfusion = Trasfusione del sangue · 2018Trial
- Trial
- Assessment of implementation of ferritin testing on donor return.Transfusion · 2026Article
- Pre-donation deferral rates and causes among whole blood and apheresis platelet donors in China: A multi-centre retrospective study (2016-2024).Vox sanguinis · 2026Article
- Sociodemographic and Lifestyle Determinants of HIF-1α Response to Blood Donation and Hematopoietic Factors: Epidemiological and Public Health Perspectives from Voluntary Donors.Epidemiologia (Basel, Switzerland) · 2026Article
- A structural deletion in the 3'UTR of SLC11A2 is associated with altered iron status: Evidence from two large Danish cohorts.British journal of haematology · 2025Article
- Limitations of the Male/Female Binary for Studying the Influences of Sex- and Gender-Related Factors on Health.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Iron deficiency and infection risk in Danish blood donors.Transfusion · 2025Article
- Article
- Menstrual blood loss is an independent determinant of hemoglobin and ferritin levels in premenopausal blood donors.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Development and validation of a prediction model for iron status in a large U.S. cohort of women.Scientific reports · 2023Article
- Pilot Study to Gain First Indications for the Impact of a 3-Month's Oral Intake of a Sucrosomial Iron Supplement on Hemoglobin in Iron-Deficient Blood Donors.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023Article
- Cohort Profile: The Danish Blood Donor Study.International journal of epidemiology · 2023Article
- A reference interval study of ferritin and transferrin levels in donors from two blood centers.Experimental and therapeutic medicine · 2023Article
- Using Capillary Whole Blood to Quantitatively Measure Ferritin: A Validation Trial of a Point-of-Care System.Nutrients · 2023Article
- Eligibility Considerations for Female Whole Blood Donors: Hemoglobin Levels and Iron Status in a Nationally Representative Population.Transfusion medicine reviews · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDietary studies show a relationship between the intake of iron enhancers and inhibitors and iron stores in the general population. However, the impact of dietary factors on the iron stores of blood donors, whose iron status is affected by blood donations, is incompletely understood. STUDY DESIGN AND
methodsIn the Danish Blood Donor Study, we assessed the effect of blood donation frequency, physiologic factors, lifestyle and supplemental factors, and dietary factors on ferritin levels. We used multiple linear and logistic regression analyses stratified by sex and menopausal status.
resultsAmong high-frequency donors (more than nine donations in the past 3 years), we found iron deficiency (ferritin below 15 ng/mL) in 9, 39, and 22% of men, premenopausal women, and postmenopausal women, respectively. The strongest predictors of iron deficiency were sex, menopausal status, the number of blood donations in a 3-year period, and the time since last donation. Other significant factors included weight, age, intensity of menstruation, iron tablets, vitamin pills, and consumption of meat and wine.
conclusionThe study confirms iron deficiency as an important problem, especially among menstruating women donating frequently. The risk of iron depletion was largely explained by sex, menopausal status, and donation frequency. Other factors, including dietary and supplemental iron intake, had a much weaker effect on the risk of iron depletion.
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