ArticleBioMed research international2013
Interval and continuous exercise training produce similar increases in skeletal muscle and left ventricle microvascular density in rats.
Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Non-Work-Matched HIIT and MIIT Partially Restore Exerkine-Related and Mitochondrial Gene Expression in Diabetic Rat Skeletal Muscle.Biomolecules · 2026Article
- Ecdysterone and High-Intensity Interval Training Mitigate Alzheimer's Pathology in Rats: Impacts on Depression, Synaptic Plasticity, and Neuroinflammation.Molecular neurobiology · 2025Article
- A user-friendly machine learning approach for cardiac structures assessment.Frontiers in cardiovascular medicine · 2024Article
- Effects of High-Intensity Interval Training and Continuous Training on Exercise Capacity, Heart Rate Variability and Isolated Hearts in Diabetic Rats.Arquivos brasileiros de cardiologia · 2023Article
- Therapeutic Effects of High-Intensity Interval Training Exercise Alone and Its Combination with Ecdysterone Against Amyloid Beta-Induced Rat Model of Alzheimer's Disease: A Behavioral, Biochemical, and Histological Study.Neurochemical research · 2022Article
- Structured pain-free exercise progressively improves ankle-brachial index and walking ability in patients with claudication and compressible arteries: an observational study.Internal and emergency medicine · 2022Observational
- Sex Differences in Spatial Learning and Memory in Valproic Acid Rat Model of Autism: Possible Beneficial Role of Exercise Interventions.Frontiers in behavioral neuroscience · 2022Article
- Cardiac basal autophagic activity and increased exercise capacity.The journal of physiological sciences : JPS · 2018Article
- Relationship between cardiac deformation parameters measured by cardiovascular magnetic resonance and aerobic fitness in endurance athletes.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2016Article
- Modulating the vascular response to limb ischemia: angiogenic and cell therapies.Circulation research · 2015Review
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Authors and funding
4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Interval training (IT), consisting of alternated periods of high and low intensity exercise, has been proposed as a strategy to induce more marked biological adaptations than continuous exercise training (CT). The purpose of this study was to assess the effects of IT and CT with equivalent total energy expenditure on capillary skeletal and cardiac muscles in rats. Wistar rats ran on a treadmill for 30 min per day with no slope (0%), 4 times/week for 13 weeks. CT has constant load of 70% max; IT has cycles of 90% max for 1 min followed by 1 min at 50% max. CT and IT increased endurance and muscle oxidative capacity and attenuated body weight gain to a similar extent (P > 0.05). In addition, CT and IT similarly increased functional capillary density of skeletal muscle (CT: 30.6 ± 11.7%; IT: 28.7 ± 11.9%) and the capillary-to-fiber ratio in skeletal muscle (CT: 28.7 ± 14.4%; IT: 40.1 ± 17.2%) and in the left ventricle (CT: 57.3 ± 53.1%; IT: 54.3 ± 40.5%). In conclusion, at equivalent total work volumes, interval exercise training induced similar functional and structural alterations in the microcirculation of skeletal muscle and myocardium in healthy rats compared to continuous exercise training.
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