Evidence map›Paper›PMID 24371711›Full record

ArticleGynecologic oncology case reports2013

Papillary serous carcinoma of the cervix mixed with squamous cells: A report of the first case.

Weiwei Tang, Zhenzhen Zhang, Hongmei Yao, Zheng Zeng, Guiping Wan

Open access · hybridAbstract read
In one paragraph

Article in Gynecologic oncology case reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. The association between expression of p53 and aggressiveness of serous adenocarcinoma of the uterine cervix.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Weiwei TangDepartment of Gynecology and Obstetrics, The Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, 100 Hongshan Road, Nanjing 210028, China.
Zhenzhen ZhangDepartment of Gynecology and Obstetrics, The Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, 100 Hongshan Road, Nanjing 210028, China.
Hongmei YaoDepartment of Gynecology and Obstetrics, The Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, 100 Hongshan Road, Nanjing 210028, China.
Zheng ZengDepartment of Pathology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, 100 Hongshan Road, Nanjing 210028, China.
Guiping WanDepartment of Gynecology and Obstetrics, The Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, 100 Hongshan Road, Nanjing 210028, China.
Jiangsu Province Hospital · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrimary papillary serous carcinoma (PPSC) of the cervix is rarely recognized, with the aggressive and unpredictable course. Here we report a case of primary adenosquamous papillary serous carcinoma of the cervix in a woman who underwent comprehensive treatment. CASE: A 53-year-old woman presented with irregular vaginal bleeding in hospital. The patient with a diagnosis of PPSC by an intracolposcopic biopsy received radical hysterectomy with bilateral salpingo-oophorectomy, right pelvic lymphadenectomy, left pelvic lymph node dissection, and postoperative concurrent chemoradiotherapy. Postoperative immunohistochemistry showed that CK5/6, CK7, P16, CEA, CA12-5 and P53 were positive. During 17 months after operation, the patient demonstrated distant metastases of lymph nodes and finally died of brain metastasis.

conclusionsPapillary serous adenocarcinoma of the cervix mixed with squamous cell carcinoma has not been reported since now, and here, this is the first documented case. Despite surgery and concurrent chemoradiotherapy, which were reported as effective therapeutic strategies for papillary serous adenocarcinoma of the cervix, the patient showed a poorer prognosis. Taken together, papillary serous adenosquamous carcinoma of the cervix could be more malignant than pure papillary serous adenocarcinoma.

Indexed as

AC, adenocarcinomaAdenosquamous carcinomaCA, cancer antigenCEA, carcinoembryonic antigenCT, computed tomographyMRI, magnetic resonance imagingPapillary serous carcinoma of the cervixPPSC, Primary papillary serous carcinomaSCC, squamous cell carcinomaTherapy

Identifiers

PMID24371711
PMCPMC3862309
OpenAlexW2027760935

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.