ReviewMediators of inflammation2013
Immunoinflammatory response in critically ill patients: severe sepsis and/or trauma.
Review in Mediators of inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Effect of prebiotics, probiotics, and synbiotics on gastrointestinal outcomes in healthy adults and active adults at rest and in response to exercise-A systematic literature review.Frontiers in nutrition · 2022Pooled it
- Efficacy and Safety of Esmolol in Treatment of Patients with Septic Shock.Chinese medical journal · 2016Trial
- Effect of Cholecalciferol Supplementation on Vitamin D Status and Cathelicidin Levels in Sepsis: A Randomized, Placebo-Controlled Trial.Critical care medicine · 2015Trial
- Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway.BMC nephrology · 2025Article
- Biomarkers of sepsis in burn injury: an update.Burns & trauma · 2025Review
- Inhibition of IL-27 signaling regulates chemokine levels and sustains CXCR2 receptor expression on mononuclear cells to improve disease outcomes during gram-negative neonatal sepsis.Frontiers in immunology · 2025Article
- The association of neutrophil-lymphocyte ratio and prognostic nutritional index with the development to chronic critical illness and their prognosis.Frontiers in nutrition · 2025Article
- Prediction of Subclinical and Clinical Multiple Organ Failure Dysfunction in Breast Cancer Patients-A Review Using AI Tools.Cancers · 2024Review
- Diagnosis and management of malaria in the intensive care unit.Journal of intensive medicine · 2024Review
- Correlation Between Low Platelet-to-Lymphocyte Ratio and High Mortality Rates in Adult Trauma Patients With Moderate-to-Severe Brain Injuries.Emergency medicine international · 2024Article
- Non-Neuronal Acetylcholinesterase Activity Shows Limited Utility for Early Detection of Sepsis.Biomedicines · 2023Article
- Therapeutic potential of mesenchymal stromal/stem cells in critical-care patients with systemic inflammatory response syndrome.Clinical and translational medicine · 2023Review
- Association of White Blood Cell Subtypes and Derived Ratios with a Mortality Outcome in Adult Patients with Polytrauma.Healthcare (Basel, Switzerland) · 2022Article
- Mean Platelet Volume to Platelet Count Ratio as a Predictor of Mortality in Unstable Pertrochanteric Fracture Treated with Short Proximal Femoral Anterograde Nail.Indian journal of orthopaedics · 2022Article
- Immunomonitoring of Monocyte and Neutrophil Function in Critically Ill Patients: From Sepsis and/or Trauma to COVID-19.Journal of clinical medicine · 2021Review
- Association of Platelets and White Blood Cells Subtypes with Trauma Patients' Mortality Outcome in the Intensive Care Unit.Healthcare (Basel, Switzerland) · 2021Article
- Evaluation of TNF-α genetic polymorphisms as predictors for sepsis susceptibility and progression.BMC infectious diseases · 2020Article
- Multiple organ dysfunction syndrome: Contemporary insights on the clinicopathological spectrum.Qatar medical journal · 2020Article
- Sepsis: Inflammation Is a Necessary Evil.Frontiers in cell and developmental biology · 2019Review
- Evaluation of BCL2 and TNFα as mRNA biomarkers for monitoring the immune response in critically ill children.Annals of medicine and surgery (2012) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunoinflammatory response in critically ill patients is very complex. This review explores some of the new elements of immunoinflammatory response in severe sepsis, tumor necrosis factor-alpha in severe acute pancreatitis as a clinical example of immune response in sepsis, immune response in severe trauma with or without secondary sepsis, and genetic aspects of host immuno-inflammatory response to various insults in critically ill patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.