Evidence map›Paper›PMID 24371024›Full record

ArticleAJNR. American journal of neuroradiology2014

Radiation doses of cerebral blood volume measurements using C-arm CT: A phantom study.

W F Chu, C J Lin, W S Chen, S C Hung, C F Chiu, T H Wu, W Y Guo

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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  3. Imaging of HCC-Current State of the Art.Diagnostics (Basel, Switzerland) · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

W F ChuFrom the Department of Radiology (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.), Taipei Veterans General Hospital, Taipei, TaiwanSchool of Medicine (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.).
C J LinFrom the Department of Radiology (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.), Taipei Veterans General Hospital, Taipei, TaiwanSchool of Medicine (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.).
W S ChenDepartment of Biomedical Imaging and Radiological Sciences (W.S.C., T.H.W.), National Yang-Ming University, Taipei, Taiwan.
S C HungFrom the Department of Radiology (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.), Taipei Veterans General Hospital, Taipei, TaiwanSchool of Medicine (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.).
C F ChiuFrom the Department of Radiology (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.), Taipei Veterans General Hospital, Taipei, TaiwanSchool of Medicine (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.).
T H WuDepartment of Biomedical Imaging and Radiological Sciences (W.S.C., T.H.W.), National Yang-Ming University, Taipei, Taiwan. wyguo@vghtpe.gov.tw tung@ym.edu.tw.
W Y GuoFrom the Department of Radiology (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.), Taipei Veterans General Hospital, Taipei, TaiwanSchool of Medicine (W.F.C., C.J.L., S.C.H., C.F.C., W.Y.G.) wyguo@vghtpe.gov.tw tung@ym.edu.tw.
Taipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeParenchymal blood volume measurement by C-arm CT facilitates in-room peritherapeutic perfusion evaluation. However, the radiation dose remains a major concern. This study aimed to compare the radiation dose of parenchymal blood volume measurement using C-arm CT with that of conventional CTP using multidetector CT. MATERIALS AND

methodsA biplane DSA equipped with C-arm CT and a Rando-Alderson phantom were used. Slab parenchymal blood volume (8-cm scanning range in a craniocaudal direction) and whole-brain parenchymal blood volume with identical scanning parameters, except for scanning ranges, were undertaken on DSA. Eighty thermoluminescent dosimeters were embedded into 22 organ sites of the phantom. We followed the guidelines of the International Commission on Radiation Protection number 103 to calculate the effective doses. For comparison, 8-cm CTP with the same phantom and thermoluminescent dosimeter distribution was performed on a multidetector CT. Two repeat dose experiments with the same scanning parameters and phantom and thermoluminescent dosimeter settings were conducted.

resultsBrain-equivalent dose in slab parenchymal blood volume, whole-brain parenchymal blood volume, and CTP were 52.29 ± 35.31, 107.51 ± 31.20, and 163.55 ± 89.45 mSv, respectively. Variations in the measurement of an equivalent dose for the lens were highest in slab parenchymal blood volume (64.5%), followed by CTP (54.6%) and whole-brain parenchymal blood volume (29.0%). The effective doses of slab parenchymal blood volume, whole-brain parenchymal blood volume, and CTP were 0.87 ± 0.55, 3.91 ± 0.78, and 2.77 ± 1.59 mSv, respectively.

conclusionsThe dose measurement conducted in the current study was reliable and reproducible. The effective dose of slab parenchymal blood volume is about one-third that of CTP. With the advantages of on-site and immediate imaging availability and saving procedural time and patient transportation, slab parenchymal blood volume measurement using C-arm CT can be recommended for clinical application.

Indexed as

Phantoms, ImagingRadiation DosageAbsorption, RadiationBlood VolumeBlood Volume DeterminationBrainCone-Beam Computed TomographyEquipment DesignEquipment Failure AnalysisHumansReproducibility of ResultsSensitivity and SpecificityThermoluminescent Dosimetry

Identifiers

PMID24371024
PMCPMC7965136
OpenAlexW2329199634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.