ArticleAmerican journal of Alzheimer's disease and other dementias2014
Observation of social behavior in frontotemporal dementia.
Article in American journal of Alzheimer's disease and other dementias, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Call for Drug Therapies for the Treatment of Social Behavior Disorders in Dementia: Systematic Review of Evidence and State of the Art.International journal of molecular sciences · 2022Pooled it
- Speech and language impairments in behavioral variant frontotemporal dementia: A systematic review.Neuroscience and biobehavioral reviews · 2021Pooled it
- Intranasal oxytocin for apathy in people with frontotemporal dementia (FOXY): a multicentre, randomised, double-blind, placebo-controlled, adaptive, crossover, phase 2a/2b superiority trial.The Lancet. Neurology · 2025Trial
- Adaptive crossover designs for assessment of symptomatic treatments targeting behaviour in neurodegenerative disease: a phase 2 clinical trial of intranasal oxytocin for frontotemporal dementia (FOXY).Alzheimer's research & therapy · 2018Trial
- Factors Associated with the Social Behaviour of People with Alzheimer's Dementia: A Video Observation Study.Brain sciences · 2025Article
- Behavioural changes in frontotemporal dementia and their cognitive and neuroanatomical correlates.Brain : a journal of neurology · 2025Article
- A neuroanatomical and cognitive model of impaired social behaviour in frontotemporal dementia.Brain : a journal of neurology · 2024Review
- A cross-sectional evaluation of acceptability of an online palliative rehabilitation program for family caregivers of people with amyotrophic lateral sclerosis and cognitive and behavioral impairments.BMC health services research · 2022Article
- Appreciation of Social Norms in Agenesis of the Corpus Callosum.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021Article
- Frontotemporal asymmetry in socioemotional behavior: A pilot study in frontotemporal dementia.Social neuroscience · 2020Article
- Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia? Review of Key Points Toward an Accurate Clinical and Neuropsychological Diagnosis.Journal of Alzheimer's disease : JAD · 2020Review
- Neurocognitive mechanisms of theory of mind impairment in neurodegeneration: a transdiagnostic approach.Neuropsychiatric disease and treatment · 2019Review
- Psychological and Cognitive Markers of Behavioral Variant Frontotemporal Dementia-A Clinical Neuropsychologist's View on Diagnostic Criteria and Beyond.Frontiers in neurology · 2019Review
- Network Architecture Underlying Basal Autonomic Outflow: Evidence from Frontotemporal Dementia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Screening for Emotional Expression in Frontotemporal Dementia: A Pilot Study.Behavioural neurology · 2018Article
- Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans.Journal of visualized experiments : JoVE · 2016Article
- Neuropsychological and Neuroanatomical Correlates of the Social Norms Questionnaire in Frontotemporal Dementia Versus Alzheimer's Disease.American journal of Alzheimer's disease and other dementias · 2016Article
- Clinical assessment of social cognitive function in neurological disorders.Nature reviews. Neurology · 2016Review
- Beyond words: Pragmatic inference in behavioral variant of frontotemporal degeneration.Neuropsychologia · 2015Article
- Processing ambiguity in a linguistic context: decision-making difficulties in non-aphasic patients with behavioral variant frontotemporal degeneration.Frontiers in human neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundThe most characteristic manifestations of behavioral variant frontotemporal dementia (bvFTD) are abnormalities in social behavior. However, distinguishing bvFTD based on social behavior can be difficult in structured clinical settings.
methodsUsing a Social Observation Inventory, 10 patients with bvFTD and 10 patients with Alzheimer's disease (AD) were compared to their caregiver interlocutors on 1-hour mealtime, in-home videotaped segments.
resultsCompared to caregivers and patients with AD, patients with bvFTD were significantly disturbed in social behavior. In contrast, patients with AD were indistinguishable from their caregivers. The lack of "you" comments and decreased tact and manners distinguished 92.6% of the patients with bvFTD from patients with AD and caregivers. The Social Observation Inventory scores correlated with scores on frontal-executive tests and socioemotional scales.
conclusionsThe systematic observation of social behavior during routine activities may be one of the best ways to distinguish patients with bvFTD from normal individuals and from patients with other dementias.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.