Evidence map›Paper›PMID 24369865›Full record

ReviewAcademic pediatrics

Genomics, personalized medicine, and pediatrics.

William Gregory Feero, Alan E Guttmacher

Abstract readReview
In one paragraph

Review in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. 21Frontiers in pediatrics · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. The genetic basis of disease.Essays in biochemistry · 2018
    Review
  8. Commentary for Special Issue of Prevention Science "Using Genetics in Prevention: Science Fiction or Science Fact?"Prevention science : the official journal of the Society for Prevention Research · 2018
    Article
  9. Pediatrics in 21Indian journal of pediatrics · 2016
    Article
  10. Article
  11. Review
  12. The Significance of an Enhanced Concept of the Organism for Medicine.Evidence-based complementary and alternative medicine : eCAM · 2016
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William Gregory FeeroMaineDartmouth Family Medicine Residency Program, Augusta, ME. Electronic address: wfeero@mainegeneral.org.
Alan E GuttmacherEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Genomic discoveries are advancing biomedicine at an ever-increasing pace. Pediatrics is near the epicenter of these discoveries, which are revising our understanding of the genome and its function. Since the completion of the Human Genome Project in 2003, dramatic reductions in the cost of genotyping, and more recently sequencing, have permitted the study of the genomes of a great number of species as well as humans. These studies have led to insights on gene regulation and the complex interplay of factors responsible for normal development and biology. Study of single-gene disorders has greatly benefited from the genomics revolution and tests are now available for well over 2000 Mendelian conditions; availability of these tests are changing screening and diagnosis paradigms for rare conditions. Genomics is also yielding an increased understanding of common conditions such as diabetes, obesity, asthma, cancers, and mental health conditions. Personalized medicine, an approach to care in which an individual's genomic information is used to help tailor interventions to maximize health outcomes, is rapidly becoming a reality for a variety of conditions. Though challenges remain in translating new genomic insights into improved patient health, today's pediatricians and their patients will increasingly benefit from this watershed moment in the biological sciences.

Indexed as

GenomicsPediatricsPrecision MedicineEpigenomicsGenotyping TechniquesHigh-Throughput Nucleotide SequencingHuman Genome ProjectHumansInfant, NewbornMicrobiotaNeonatal ScreeningOligonucleotide Array Sequence AnalysisPharmacogeneticsPolymorphism, Single Nucleotidegeneticsgenomicsgenotypingpediatricspersonalized medicinesequencing

Identifiers

PMID24369865
PMCPMC4227880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.