Evidence map›Paper›PMID 24369796›Full record

ReviewThe Journal of allergy and clinical immunology2014

Researching asthma across the ages: insights from the National Heart, Lung, and Blood Institute's Asthma Network.

Michael D Cabana, Susan J Kunselman, Sharmilee M Nyenhuis, Michael E Wechsler

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. A comparison of tiotropium, long-acting βRespiratory research · 2020
    Review
  6. Article
  7. Review
  8. Article
  9. Integrated genomic analysis suggests MLL3 is a novel candidate susceptibility gene for familial nasopharyngeal carcinoma.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Article
  10. Article
  11. Advances in pediatric asthma in 2013: coordinating asthma care.The Journal of allergy and clinical immunology · 2014
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Michael D CabanaDepartments of Pediatrics, Epidemiology, and Biostatistics and the Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, Calif. Electronic address: michael.cabana@ucsf.edu.
Susan J KunselmanMilton S. Hershey College of Medicine, Hershey, Pa.
Sharmilee M NyenhuisDivision of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois Hospital and Health Sciences System, Chicago, Ill.
Michael E WechslerDepartment of Medicine, National Jewish Health, Denver, Colo.
Hershey (United States) · USUniversity of California, San Francisco · USUniversity of Colorado Denver · USUniversity of Illinois Hospital & Health Sciences System · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet)U10HL098115 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2009 to 2015
$57.6M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
Clinical Centers for the NHLBI Asthma Network (AsthmaNet)U10HL098075 · NHLBI · NATIONAL JEWISH HEALTH · PI SZEFLER, STANLEY J., WECHSLER, MICHAEL E · 2009 to 2015
$5.1M
AsthmaNet: UW-Madison Clinical and Translational Research CenterU10HL098090 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SORKNESS, CHRISTINE ANNE · 2009 to 2015
$4.8M
UCSF AsthmaNet Clinical CenterU10HL098107 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CABANA, MICHAEL D, LAZARUS, STEPHEN C · 2009 to 2015
$4.8M
Chicagoland Metropolitan AsthmaNet Consortium (CMAC)U10HL098096 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KRISHNAN, JERRY A., PONGRACIC, JACQUELINE · 2009 to 2015
$4.6M
Washington University AsthmaNetU10HL098098 · NHLBI · WASHINGTON UNIVERSITY · PI BACHARIER, LEONARD B, CASTRO, MARIO · 2009 to 2015
$4.5M
NCATS NIH HHS UL1 TR000004NCRR NIH HHS UL1 RR024131NHLBI NIH HHS HL098115NHLBI NIH HHS U10 HL098075NHLBI NIH HHS U10 HL098090NHLBI NIH HHS U10 HL098096NHLBI NIH HHS U10 HL098098NHLBI NIH HHS U10 HL098102NHLBI NIH HHS U10 HL098107NHLBI NIH HHS U10 HL098115
6 · The paper itself

Abstract

Clinical asthma studies across different age groups (ie, cross-age studies) can potentially offer insight into the similarities, differences, and relationships between childhood and adult asthma. The National Institutes of Health's Asthma Research Network (AsthmaNet) is unique and innovative in that it has merged pediatric and adult asthma research into a single clinical research network. This combination enhances scientific exchange between pediatric and adult asthma investigators and encourages the application of cross-age studies that involve participants from multiple age groups who are generally not studied together. The experience from AsthmaNet in the development of cross-age protocols highlights some of the issues in the evaluation of cross-age research in asthma. The aim of this review is to summarize these challenges, including the selection of parallel cross-age clinical interventions, identification of appropriate controls, measurement of meaningful clinical outcomes, and various ethical and logistic issues.

Indexed as

AdultAge FactorsAnti-Asthmatic AgentsAsthmaChildFemaleHumansMaleNational Heart, Lung, and Blood Institute (U.S.)Population GroupsTreatment OutcomeUnited StatesAnti-Asthmatic AgentsACTAsthmaAsthma Control TestBARDBest African-American Response to Asthma DrugscACTChildhood Asthma Control Testclinical trialsFDAICSInhaled corticosteroidInstitutional review boardIRBLABALong-acting β-agonistNational Heart, Lung, and Blood InstituteNHLBIoutcome measuresparticipant recruitmentpediatric assentpediatric consentQOLQuality of lifestudy designUS Food and Drug AdministrationVIDAVitamin D Add-on Therapy Enhances Corticosteroid Responsiveness in Asthma

Identifiers

PMID24369796
PMCPMC3901784
OpenAlexW2094453121

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.