ArticleJournal of the International AIDS Society2013
Antiretroviral treatment and quality of life in Africans living with HIV: 12-month follow-up in Burkina Faso.
Article in Journal of the International AIDS Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- What constitutes a palliative care need in people with serious illnesses across Africa? A mixed-methods systematic review of the concept and evidence.Palliative medicine · 2021Pooled it
- An Interactive Voice Response Software to Improve the Quality of Life of People Living With HIV in Uganda: Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings.AIDS care · 2018Trial
- Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women.AIDS (London, England) · 2018Trial
- Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study.PloS one · 2015Trial
- Identifying risk factors for adverse drug reactions in HIV/AIDS patients using LASSO regression modeling.BMC infectious diseases · 2026Article
- Mapping health-related quality of life measurement tools in Africa: a scoping review.Journal of patient-reported outcomes · 2026Article
- Trajectories of health-related quality of life among people with HIV within five years of diagnosis.BMC psychology · 2025Article
- Incidence of Adverse Drug Reactions Among HIV Patients on Antiretroviral Drugs in Ethiopia: A Systematic Review and Meta-Analysis.AIDS research and treatment · 2025Review
- Effect of status disclosure on quality of life among people living with HIV/AIDS in Ghana: A health facility-based cross-sectional study.PLOS mental health · 2024Article
- Longitudinal trajectory of the association between quality of life and depression among people living with HIV in China: a mixed effects model.AIDS care · 2022Article
- Article
- The effect of TB treatment on health-related quality of life for people with advanced HIV.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2020Article
- Changes and determinants of health-related quality of life among people newly diagnosed with HIV in China: a 1-year follow-up study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Advantages of Chinese Medicine for Patients with Acquired Immunodeficiency Syndrome in Rural Central China.Chinese journal of integrative medicine · 2018Article
- Oral health and health-related quality of life in HIV patients.BMC oral health · 2018Article
- Association among oral symptoms, oral health-related quality of life, and health-related quality of life in a sample of adults living with HIV/AIDS in Malaysia.BMC oral health · 2017Article
- Quality of life in persons living with HIV in Burkina Faso: a follow-up over 12 months.BMC public health · 2015Article
- Bioinformatics in Africa: The Rise of Ghana?PLoS computational biology · 2015Article
- Quality of life in people living with HIV: a cross-sectional study in Ouagadougou, Burkina Faso.SpringerPlus · 2014Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
introductionThe scale-up of highly active antiretroviral therapy (HAART) has led to a significant improvement in survival of the HIV-positive patient but its effects on health-related quality of life (HRQOL) are less known and context-dependent. Our aim was to assess the temporal changes and factors associated with HRQOL among HIV-positive adults initiating HAART in Burkina Faso.
methodsHIV-positive people initiating HAART were prospectively included and followed over a one-year period in three HIV clinics of Ouagadougou. HRQOL was assessed at baseline and at each follow-up visit using physical (PHS) and mental (MHS) summary scores derived from the Medical Outcome Study 36-Item short-form health survey (MOS SF-36) questionnaire. Toxicity related to HAART modification and self-reported symptoms were recorded during follow-up visits. Determinants associated with baseline and changes in both scores over a one-year period were assessed using a mixed linear model.
resultsA total of 344 patients were included. Their median age at baseline was 37 years [interquartile range (IQR) 30-44] and their median CD4 count was 181 cells/mm(3) (IQR 97-269). The mean [standard deviation (SD)] PHS score increased from 45.4 (11.1) at baseline to 60.0 (3.1) at 12 months (p <10(-4)) and the mean (SD) MHS score from 42.2 (8.7) to 43.9 (3.4) (p<10(-2)). After one year of treatment, patients that experienced on average two symptoms during follow-up presented with significantly lower PHS (63.9) and MHS (43.8) scores compared to patients that presented no symptoms with PHS and MHS of 68.2 (p<10(-4)) and 45.3 (p<10(-3)), respectively. DISCUSSION: The use of HAART was associated with a significant increase in both physical and mental aspects of the HRQOL over a 12-month period in this urban African population. Perceived symptoms experienced during follow-up visits were associated with a significant impairment in HRQOL. The appropriate and timely management of reported symptoms during the follow-up of HAART-treated patients is a key component to restore HRQOL.
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