ReviewAsian journal of andrology
Maternal cigarette smoking during pregnancy and reproductive health in children: a review of epidemiological studies.
Review in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Maternal smoking during pregnancy and the risk of congenital urogenital malformations: A systematic review and meta-analysis.Frontiers in pediatrics · 2022Pooled it
- Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis.Environmental health and preventive medicine · 2018Pooled it
- Parity and bladder cancer risk: a dose-response meta-analysis.BMC cancer · 2017Pooled it
- Pooled it
- Maternal organophosphate esters and sex steroid hormones in mid-pregnancy.Environmental research · 2025Article
- Etiology of Male Infertility: an Update.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Updating an Overview of Teratology.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Bibliometric analysis of scientific publications on cryptorchidism: Research hotspots and trends between 2000 and 2022.Heliyon · 2023Article
- An Overview of E-Cigarette Impact on Reproductive Health.Life (Basel, Switzerland) · 2023Review
- Maternal Exposure to Cigarette Smoke during Pregnancy and Testicular Cancer in Offspring: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2023Review
- The undescended testis in children and adolescents. Part 1: pathophysiology, classification, and fertility- and cancer-related controversies.Pediatric surgery international · 2022Review
- The undescended testis in children and adolescents part 2: evaluation and therapeutic approach.Pediatric surgery international · 2022Review
- Fetal exposure to maternal cigarette smoking and male reproductive function in young adulthood.European journal of epidemiology · 2022Article
- Maternal Cigarette Smoking During Pregnancy and Genital Anomalies in Boys: A Register-Based Cohort and Sibling-Matched Design Study.Clinical epidemiology · 2022Article
- Recalled maternal lifestyle behaviors associated with anti-müllerian hormone of adult female offspring.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
- Association between factors related to the pregnancy, neonatal period, and later complications (especially asthma) and menarcheal age in a sample of Lebanese girls.BMC women's health · 2020Article
- Smoking cessation in early-pregnancy, gestational weight gain and subsequent risks of pregnancy complications.European journal of obstetrics, gynecology, and reproductive biology · 2020Article
- Why Do Intrauterine Exposure to Air Pollution and Cigarette Smoke Increase the Risk of Asthma?Frontiers in cell and developmental biology · 2020Review
- Regional difference in semen quality of young men: a review on the implication of environmental and lifestyle factors during fetal life and adulthood.Basic and clinical andrology · 2020Review
- Fetal and Postnatal Nicotine Exposure Modifies Maturation of Gonocytes to Spermatogonia in Mice.Analytical cellular pathology (Amsterdam) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal cigarette smoking may affect the intrauterine hormonal environment during pregnancy and this early fetal exposure may have detrimental effects on the future trajectory of reproductive health. In this review, we discuss the epidemiological literature on the association between prenatal exposure to maternal cigarette smoking and several aspects of reproductive health. The literature points towards an increased risk of the urogenital malformation cryptorchidism, but a potential protective effect on the risk of hypospadias in sons following prenatal cigarette smoking exposure. Studies on sexual maturation find a tendency towards accelerated pubertal development in exposed boys and girls. In adult life, prenatally exposed men have impaired semen quality compared with unexposed individuals, but an influence on fecundability, that is, the biological ability to reproduce, is less evident. We found no evidence to support an association between prenatal cigarette smoking exposure and testicular cancer. Among adult daughters, research is sparse and inconsistent, but exposure to cigarette smoking in utero may decrease fecundability. In conclusion, prenatal exposure to cigarette smoking may cause some long-term adverse effects on the reproductive health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.