ReviewJournal of ophthalmology2013
Smoking and age-related macular degeneration: review and update.
Review in Journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04779411 (Validation of a Lutein and Zeaxanthin Food Frequency Questionnaire, and an Electronic Device Use Questionnaire.), which is not on this map. Cited by 123 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Lutein and Zeaxanthin Food Frequency Questionnaire, and an Electronic Device Use Questionnaire.
Who cites it
123 citing papers in PubMed, 8 syntheses or guidelines pooled it, 209 citations in OpenAlex.
- Tobacco smoking is not associated with primary open-angle glaucoma: a systematic review and meta-analysis.International ophthalmology · 2026Pooled it
- National, regional, and provincial prevalence of age-related macular degeneration in China in 2020: an updated systematic review and modelling study.Journal of global health · 2026Pooled it
- Risk factors for age-related macular degeneration: an umbrella analysis of systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- [Risk factors for age-related macular degeneration : Lessons learned from current data].Die Ophthalmologie · 2025Pooled it
- Risk factors for wet macular degeneration: a systematic review, with novel insights from the Scottish Heart Health Extended Cohort.BMC ophthalmology · 2025Pooled it
- Pooled it
- Association of dry eye disease with smoking: A systematic review and meta-analysis.Indian journal of ophthalmology · 2022Pooled it
- Association Between Visual Impairment and Depression in Patients Attending Eye Clinics: A Meta-analysis.JAMA ophthalmology · 2021Pooled it
- The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence - OMEGA report 3.Acta ophthalmologica · 2026Article
- Article
- Article
- Insights into the modulation of age-related macular degeneration: Molecular and systems-level perspectives.Acta ophthalmologica · 2026Article
- The impact of systemic long-term medications for the development of age-related macular degeneration.Acta ophthalmologica · 2026Article
- ApoE- and Cfh-deficient mice exhibit structural and molecular features of human early-intermediate retinal degeneration.Animal models and experimental medicine · 2026Article
- Risk factors for age-related macular degeneration.Die Ophthalmologie · 2026Review
- Human retinal organoid model of disease-relevant photoreceptor cell death amenable to drug screening.Cell death & disease · 2026Article
- Article
- Retinal pigment epithelium pathology in age-related macular degeneration: mitigation with melatonin.Frontiers in medicine · 2026Review
- Luteolin alleviates angiogenesis in HUVECs by inhibiting VEGFA expression: integrating network pharmacology and experimental validation.Scientific reports · 2025Article
- Title Oxidative Stress in Age-Related Macular Degeneration: From Molecular Mechanisms to Emerging Therapeutic Targets.Antioxidants (Basel, Switzerland) · 2025Review
63 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Age-related macular degeneration (AMD) is one of the main socioeconomical health issues worldwide. AMD has a multifactorial etiology with a variety of risk factors. Smoking is the most important modifiable risk factor for AMD development and progression. The present review summarizes the epidemiological studies evaluating the association between smoking and AMD, the mechanisms through which smoking induces damage to the chorioretinal tissues, and the relevance of advising patients to quit smoking for their visual health.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.