Evidence map›Paper›PMID 24368935›Full record

ArticleWorld journal of gastrointestinal endoscopy2013

Finding the solution for incomplete small bowel capsule endoscopy.

José Cotter, Francisca Dias de Castro, Joana Magalhães, Maria João Moreira, Bruno Rosa

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Prolonged Gastric Transit Time in Small-Bowel Capsule Endoscopy: Which Patients Are at Risk and What Are the Implications?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
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  12. Capsule endoscopy in Portugal.Annals of translational medicine · 2017
    Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

José CotterJosé Cotter, Francisca Dias de Castro, Joana Magalhães, Maria João Moreira, Bruno Rosa, Gastroenterology Department, Centro Hospitalar do Alto Ave, 4835-044 Guimarães, Portugal.
Francisca Dias de CastroJosé Cotter, Francisca Dias de Castro, Joana Magalhães, Maria João Moreira, Bruno Rosa, Gastroenterology Department, Centro Hospitalar do Alto Ave, 4835-044 Guimarães, Portugal.
Joana MagalhãesJosé Cotter, Francisca Dias de Castro, Joana Magalhães, Maria João Moreira, Bruno Rosa, Gastroenterology Department, Centro Hospitalar do Alto Ave, 4835-044 Guimarães, Portugal.
Maria João MoreiraJosé Cotter, Francisca Dias de Castro, Joana Magalhães, Maria João Moreira, Bruno Rosa, Gastroenterology Department, Centro Hospitalar do Alto Ave, 4835-044 Guimarães, Portugal.
Bruno RosaJosé Cotter, Francisca Dias de Castro, Joana Magalhães, Maria João Moreira, Bruno Rosa, Gastroenterology Department, Centro Hospitalar do Alto Ave, 4835-044 Guimarães, Portugal.
Centro de Computação Gráfica · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate whether the use of real time viewer (RTV) and administration of domperidone to patients with delayed gastric passage of the capsule could reduce the rate of incomplete examinations (IE) and improve the diagnostic yield of small bowel capsule endoscopy (SBCE).

methodsProspective single center interventional study, from June 2012 to February 2013. Capsule location was systematically checked one hour after ingestion using RTV. If it remained in the stomach, the patient received 10 mg domperidone per os and the location of the capsule was rechecked after 30 min. If the capsule remained in the stomach a second dose of 10 mg of domperidone was administered orally. After another 30 min the position was rechecked and if the capsule remained in the stomach, it was passed into the duodenum by upper gastrointestinal (GI) endoscopy. The rate of IE and diagnostic yield of SBCE were compared with those of examinations performed before the use of RTV or domperidone in our Department (control group, January 2009 - May 2012).

resultsBoth groups were similar regarding age, sex, indication, inpatient status and surgical history. The control group included 307 patients, with 48 (15.6%) IE. The RTV group included 82 patients, with 3 (3.7%) IE, P = 0.003. In the control group, average gastric time was significantly longer in patients with IE than in patients with complete examination of the small bowel (77 min vs 26 min, P = 0.003). In the RTV group, the capsule remained in the stomach one hour after ingestion in 14/82 patients (17.0%) vs 48/307 (15.6%) in the control group, P = 0.736. Domperidone did not significantly affect small bowel transit time (260 min vs 297 min, P = 0.229). The capsule detected positive findings in 39% of patients in the control group and 49% in the RTV group (P = 0.081).

conclusionThe use of RTV and selective administration of domperidone to patients with delayed gastric passage of the capsule significantly reduces incomplete examinations, with no effect on small bowel transit time or diagnostic yield.

Indexed as

DomperidoneIncomplete examinationProkinetic drugsSmall bowel capsule endoscopy

Identifiers

PMID24368935
PMCPMC3870913
OpenAlexW2124710389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.