ReviewFrontiers in plant science2013
Exploring the role of lipids in intercellular conduits: breakthroughs in the pipeline.
Review in Frontiers in plant science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Breaking cellular boundaries: molecular mechanisms of tunneling nanotube formation and fusion.Biochemical Society transactions · 2026Review
- CD13 activation assembles phosphoinositide (PI) signaling complexes to regulate the actin cytoskeleton.Scientific reports · 2026Article
- Article
- Molecular, morphological and functional properties of tunnelling nanotubes between normal and cancer urothelial cells: New insights from theFrontiers in cell and developmental biology · 2022Article
- Peering into tunneling nanotubes-The path forward.The EMBO journal · 2021Review
- Membrane nanotubes are ancient machinery for cell-to-cell communication and transport. Their interference with the immune system.Biologia futura · 2021Review
- Article
- Review
- Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.Frontiers in molecular neuroscience · 2017Review
- Drosophila cells use nanotube-like structures to transfer dsRNA and RNAi machinery between cells.Scientific reports · 2016Article
- Sterols Modulate Cell-to-Cell Connectivity at Plasmodesmata.The Plant cell · 2015Article
- Specific membrane lipid composition is important for plasmodesmata function in Arabidopsis.The Plant cell · 2015Article
- Trypanosoma cruzi invasion is associated with trogocytosis.Microbes and infection · 2015Article
- Specialized membrane domains of plasmodesmata, plant intercellular nanopores.Frontiers in plant science · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been known for more than a century that most of the plant cells are connected to their neighbors through membranous pores perforating the cell wall, namely plasmodesmata (PDs). The recent discovery of tunneling nanotubes (TNTs), thin membrane bridges established between distant mammalian cells, suggests that intercellular communication mediated through cytoplasmic continuity could be a conserved feature of eukaryotic organisms. Although TNTs differ from PDs in their formation and architecture, both are characterized by a continuity of the plasma membrane between two cells, delimiting a nanotubular channel supported by actin-based cytoskeleton. Due to this unusual membrane organization, lipids are likely to play critical roles in the formation and stability of intercellular conduits like TNTs and PDs, but also in regulating the transfer through these structures. While it is crucial for a better understanding of those fascinating communication highways, the study of TNT lipid composition and dynamics turned out to be extremely challenging. The present review aims to give an overview of the recent findings in this context. We will also discuss some of the promising imaging approaches, which might be the key for future breakthroughs in the field and could also benefit the research on PDs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.