Evidence map›Paper›PMID 24368878›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2014

Influence of microkeratome parameters on the stromal bed and flap edge quality in laser in situ keratomileusis.

Jens Heichel, Frank Wilhelm, Kathleen S Kunert, Rabea Schlueter, Ute Stuhltraeger, Thomas Hammer

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jens HeichelDepartment of Ophthalmology, University Hospital of Martin Luther University Halle/Wittenberg, Halle (Saale), Germany.
Frank WilhelmAugen im Zentrum, Greifswald, Germany.
Kathleen S KunertDepartment of Ophthalmology, Helios Klinikum Erfurt, Erfurt, Germany.
Rabea SchlueterInstitute of Microbiology, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Ute StuhltraegerDepartment of Ophthalmology, University Hospital of Martin Luther University Halle/Wittenberg, Halle (Saale), Germany.
Thomas HammerAugenzentrum Frohe Zukunft, Halle (Saale), Germany.
Martin Luther University Halle-Wittenberg · DEHelios Klinikum Erfurt · DEUniversität Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFemtosecond lasers have become the standard for laser-assisted in situ keratomileusis (LASIK) flap creation, but advanced mechanical microkeratomes are still an alternative, more cost-effective way to create the flap. The SCHWIND Carriazo-Pendular microkeratome is one of the most commonly used microkeratomes. The influence of different cutting parameters (head-advance speeds, cutting heads) on morphology of LASIK cuts was investigated.

settingExperimental study performed at the University Eye Hospital of the Martin Luther University Halle/Wittenberg, Halle (Saale), Germany.

methodsThe Carriazo-Pendular microkeratome was used on freshly enucleated porcine eyes for lamellar keratotomy. After flap removal, the cutting edge and stromal bed were evaluated from scanning electron micrographs using an individualized scoring system. Four different settings of microkeratome parameters were compared. For each setting, eight cuts were evaluated (n=32).

resultsDifferent oscillation frequencies and head-advance speeds did not influence the cutting qualities. A higher oscillation/feed rate ratio seemed to be advantageous for a smoother interface. Concerning different cuttings heads, a deeper keratotomy led to sharper cutting edges. The thinner the flap, the more irregularities in the stromal bed appeared. Complications did not occur.

conclusionThe Carriazo-Pendular microkeratome is a safe tool with which to create a LASIK flap and is a good alternative to a costly femtosecond laser. Deeper keratotomies, as well as the use of a higher oscillation/feed rate quotient, improve the cutting quality.

Indexed as

Descemet’s stripping automated endothelial keratoplasty (DSAEK)laser-assisted in situ keratomileusis (LASIK)microkeratomescanning electron microscopy (SEM)stromal bed qualitysurface regularity

Identifiers

PMID24368878
PMCPMC3869919
OpenAlexW2036724995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.