ArticleThe Plant cell2013
The trans-acting short interfering RNA3 pathway and no apical meristem antagonistically regulate leaf margin development and lateral organ separation, as revealed by analysis of an argonaute7/lobed leaflet1 mutant in Medicago truncatula.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 88 citations in OpenAlex.
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- Genome-wide identification, characterization and expression analysis of key gene families in RNA silencing in centipedegrass.BMC genomics · 2024Article
- The Biosynthesis Process of Small RNA and Its Pivotal Roles in Plant Development.International journal of molecular sciences · 2024Review
- miR-129 Regulates Yak Intramuscular Preadipocyte Proliferation and Differentiation through the PI3K/AKT Pathway.International journal of molecular sciences · 2024Article
- Identification of potential auxin response candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.Frontiers in plant science · 2024Article
- Identification of potential Auxin Response Candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.bioRxiv : the preprint server for biology · 2023Article
- Roles of very long-chain fatty acids in compound leaf patterning in Medicago truncatula.Plant physiology · 2023Article
- Identification and characterization of miRNAs and PHAS loci related to the early development of the embryo and endosperm in Fragaria × ananassa.BMC genomics · 2022Article
- Melon shoot organization 1, encoding an AGRONAUTE7 protein, plays a crucial role in plant development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Multidimensional Gene Regulatory Landscape of Motor Organ Pulvinus in the Model LegumeInternational journal of molecular sciences · 2022Article
- The Multiverse of Plant Small RNAs: How Can We Explore It?International journal of molecular sciences · 2022Review
- LATE MERISTEM IDENTITY1 regulates leaf margin development via the auxin transporter gene SMOOTH LEAF MARGIN1.Plant physiology · 2021Article
- Review
- Auxin Response Factor 2 (ARF2), ARF3, and ARF4 Mediate Both Lateral Root and Nitrogen Fixing Nodule Development inFrontiers in plant science · 2021Article
- The Genetic Control of the Compound Leaf Patterning inFrontiers in plant science · 2021Review
- Genome-Wide Identification and Evolutionary Analysis of Argonaute Genes in Hexaploid Bread Wheat.BioMed research international · 2021Article
- Article
- Developmental Genetics of Corolla Tube Formation: Role of the tasiRNA-The Plant cell · 2020Article
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leaf shape elaboration and organ separation are critical for plant morphogenesis. We characterized the developmental roles of lobed leaflet1 by analyzing a recessive mutant in the model legume Medicago truncatula. An ortholog of Arabidopsis thaliana argonaute7 (AGO7), Mt-AGO7/lobed leaflet1, is required for the biogenesis of a trans-acting short interfering RNA (ta-siRNA) to negatively regulate the expression of auxin response factors in M. truncatula. Loss of function in AGO7 results in pleiotropic phenotypes in different organs. The prominent phenotype of the ago7 mutant is lobed leaf margins and more widely spaced lateral organs, suggesting that the trans-acting siRNA3 (TAS3) pathway negatively regulates the formation of boundaries and the separation of lateral organs in M. truncatula. Genetic interaction analysis with the smooth leaf margin1 (slm1) mutant revealed that leaf margin formation is cooperatively regulated by the auxin/SLM1 (ortholog of Arabidopsis PIN-formed1) module, which influences the initiation of leaf margin teeth, and the TAS3 ta-siRNA pathway, which determines the degree of margin indentation. Further investigations showed that the TAS3 ta-siRNA pathway and no apical meristem (ortholog of Arabidopsis cup-shaped cotyledon) antagonistically regulate both leaf margin development and lateral organ separation, and the regulation is partially dependent on the auxin/SLM1 module.
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