ArticleThe Plant cell2013
Autophagy-related proteins are required for degradation of peroxisomes in Arabidopsis hypocotyls during seedling growth.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
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Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Selective autophagy of intracellular organelles: recent research advances.Theranostics · 2021Pooled it
- Cryo-SEM and large volume FIB-SEM of Arabidopsis cotyledons: Degradation of lipid bodies, biogenesis of glyoxysomes and reorganisation of organelles during germination.Journal of microscopy · 2025Article
- Pexophagy and Oxidative Stress: Focus on Peroxisomal Proteins and Reactive Oxygen Species (ROS) Signaling Pathways.Antioxidants (Basel, Switzerland) · 2025Review
- Myotubularin 2 interacts with SEC23A and negatively regulates autophagy at ER exit sites in Arabidopsis.Autophagy · 2025Article
- Vacuolar degradation of plant organelles.The Plant cell · 2024Review
- Integrated Multi-Omics Analyses Reveal That Autophagy-Mediated Cellular Metabolism Is Required for the Initiation of Pollen Germination.International journal of molecular sciences · 2023Article
- Autophagic degradation of membrane-bound organelles in plants.Bioscience reports · 2023Review
- The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy inFrontiers in plant science · 2023Article
- Defects in autophagy lead to selective in vivo changes in turnover of cytosolic and organelle proteins in Arabidopsis.The Plant cell · 2022Article
- Plant peroxisome proteostasis-establishing, renovating, and dismantling the peroxisomal proteome.Essays in biochemistry · 2022Review
- Regulation of Autophagy Machinery inInternational journal of molecular sciences · 2022Review
- Autophagy-Mediated Regulation of Different Meristems in Plants.International journal of molecular sciences · 2022Review
- Exploring the Contribution of Autophagy to the Excess-Sucrose Response inInternational journal of molecular sciences · 2022Article
- Autophagy is required for self-incompatible pollen rejection in two transgenic Arabidopsis thaliana accessions.Plant physiology · 2022Article
- Autophagy inducers lead to transient accumulation of autophagosomes in Arabidopsis roots.Plant cell reports · 2022Article
- A glossary of plant cell structures: Current insights and future questions.The Plant cell · 2022Review
- FYVE2, a phosphatidylinositol 3-phosphate effector, interacts with the COPII machinery to control autophagosome formation in Arabidopsis.The Plant cell · 2022Article
- Image-Based Analysis Revealing the Molecular Mechanism of Peroxisome Dynamics in Plants.Frontiers in cell and developmental biology · 2022Review
- Peroxisomes as redox-signaling nodes in intracellular communication and stress responses.Plant physiology · 2021Review
- How Lipids Contribute to Autophagosome Biogenesis, a Critical Process in Plant Responses to Stresses.Cells · 2021Review
9 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant peroxisomes play a pivotal role during postgerminative growth by breaking down fatty acids to provide fixed carbons for seedlings before the onset of photosynthesis. The enzyme composition of peroxisomes changes during the transition of the seedling from a heterotrophic to an autotrophic state; however, the mechanisms for the degradation of obsolete peroxisomal proteins remain elusive. One candidate mechanism is autophagy, a bulk degradation pathway targeting cytoplasmic constituents to the lytic vacuole. We present evidence supporting the autophagy of peroxisomes in Arabidopsis thaliana hypocotyls during seedling growth. Mutants defective in autophagy appeared to accumulate excess peroxisomes in hypocotyl cells. When degradation in the vacuole was pharmacologically compromised, both autophagic bodies and peroxisomal markers were detected in the wild-type vacuole but not in that of the autophagy-incompetent mutants. On the basis of the genetic and cell biological data we obtained, we propose that autophagy is important for the maintenance of peroxisome number and cell remodeling in Arabidopsis hypocotyls.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.