Evidence map›Paper›PMID 24368640›Full record

Trial reportAnnals of surgery2014

Endoscopic harvesting device type and outcomes in patients undergoing coronary artery bypass surgery.

Sean van Diepen, J Matthew Brennan, Gail E Hafley, Eric M Reyes, Keith B Allen, T Bruce Ferguson, Eric D Peterson, Judson B Williams, C Michael Gibson, Michael J Mack and 3 more

Abstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Annals of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Mechanotransduction in Coronary Vein Graft Disease.Frontiers in cardiovascular medicine · 2018
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sean van Diepen*Division of Critical Care and Cardiology, University of Alberta, Edmonton, Alberta, Canada †Duke Clinical Research Institute, Duke University Medical Center, Durham, NC ‡Mid America Heart Institute, St. Luke's Hospital, Kansas City, MO §East Carolina University, Greenville, NC ¶PERFUSE Angiographic Laboratory, Boston, MA ‖Baylor Healthcare System, Dallas, TX **Missouri Baptist Medical Center, St. Louis, MO.
J Matthew Brennan
Gail E Hafley
Eric M Reyes
Keith B Allen
T Bruce Ferguson
Eric D Peterson
Judson B Williams
C Michael Gibson
Michael J Mack
Nicholas T Kouchoukos
John H Alexander
Renato D Lopes

Funding

Core Clinical Centers for the CTSNUM1HL088953 · NHLBI · DUKE UNIVERSITY · PI SMITH, PETER K · 2013 to 2017
$2.5M
NHLBI NIH HHS UM1 HL088953
6 · The paper itself

Abstract

objectiveTo evaluate angiographic and clinical outcomes associated with open and closed dissection tunnel endoscopic vein harvesting (EVH) devices.

backgroundA previous PREVENT-IV (PRoject of Ex-vivo Vein graft ENgineering via Transfection IV) analysis reported that EVH for coronary artery bypass graft surgery was associated with worse outcomes than with traditional vein harvesting; however, outcomes by EVH device type were not available.

methodsUsing data from the PREVENT-IV trial, we compared 1549 patients from 75 surgical sites who underwent EVH with open (n = 390) or closed (n = 1159) harvest tunnel devices. Outcomes included the incidence of vein graft failure at 12 to 18 months and a composite of death, myocardial infarction, and revascularization through 5 years.

resultsAmong patients undergoing open and closed tunnel EVH, no difference in the per-patient incidence of vein graft failure (43.8% vs 47.1%; adjusted odds ratio, 0.91; 95% confidence interval, 0.53-1.55; P = 0.724) or per-graft incidence of vein graft failure (25.5% vs 25.9%; adjusted odds ratio, 0.96; 95% confidence interval, 0.59-1.55; P = 0.847) was observed. At 5 years, no difference was observed in the primary composite clinical outcome between patients who underwent open and closed system EVH (21.5% vs 23.9%; adjusted hazard ratio, 0.85; 95% confidence interval, 0.66-1.10; P = 0.221).

conclusionsNo differences in angiographic or clinical outcomes were observed among patients who underwent open versus closed tunnel endoscopic harvesting for coronary bypass surgery. These findings suggest that the risks associated with EVH that were reported in a previous PREVENT-IV analysis are not related to a specific EVH device.

Indexed as

Coronary Artery BypassAdolescentAdultAgedAged, 80 and overCoronary AngiographyDouble-Blind MethodEndoscopyFemaleGraft Occlusion, VascularGraft SurvivalHumansIncidenceMaleMiddle AgedSaphenous Vein

Identifiers

PMID24368640
PMCPMC4322758

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.