ReviewAnnals of surgery2014
Metabolic thrift and the genetic basis of human obesity.
Review in Annals of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Potential Epigenetic Impacts of Phytochemicals on Ruminant Health and Production: Connecting Lines of Evidence.Animals : an open access journal from MDPI · 2025Review
- Developmental Programming of the Fetal Immune System by Maternal Western-Style Diet: Mechanisms and Implications for Disease Pathways in the Offspring.International journal of molecular sciences · 2024Review
- When the "satisficing" is the new "fittest": how a proscriptive definition of adaptation can change our view of cognition and culture.Die Naturwissenschaften · 2022Article
- Review
- Association and interaction of the FTO rs1421085 with overweight/obesity in a sample of Pakistani individuals.Eating and weight disorders : EWD · 2020Article
- Early in life effects and heredity: reconciling neo-Darwinism with neo-Lamarckism under the banner of the inclusive evolutionary synthesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice.Molecular metabolism · 2017Article
- International society of sports nutrition position stand: diets and body composition.Journal of the International Society of Sports Nutrition · 2017Review
- Biphasic alterations in coronary smooth muscle Ca(2+) regulation in a repeat cross-sectional study of coronary artery disease severity in metabolic syndrome.Atherosclerosis · 2016Article
- Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways.Scientific reports · 2016Article
- Physiological adaptations to weight loss and factors favouring weight regain.International journal of obesity (2005) · 2015Review
- Anti-ghrelin antibodies in appetite suppression: recent advances in obesity pharmacotherapy.ImmunoTargets and therapy · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Evolution has molded metabolic thrift within humans, a genetic heritage that, when thrust into our modern "obesogenic" environment, creates the current obesity crisis. Modern genetic analysis has identified genetic and epigenetic contributors to obesity, an understanding of which will guide the development of environmental, pharmacologic, and genetic therapeutic interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.