Evidence map›Paper›PMID 24368095›Full record

ArticleJournal of molecular and cellular cardiology2014

RETRACTED: Akt2 knockout alleviates prolonged caloric restriction-induced change in cardiac contractile function through regulation of autophagy.

Yingmei Zhang, Xuefeng Han, Nan Hu, Anna F Huff, Feng Gao, Jun Ren

RetractedErratum issuedOpen access · greenAbstract readRetracted Publication
In one paragraph

Article in Journal of molecular and cellular cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Antioxidants & redox signaling · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals.Journal of molecular and cellular cardiology · 2016
    Review
  10. Article
  11. Functions of autophagy in pathological cardiac hypertrophy.International journal of biological sciences · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yingmei ZhangDepartment of Cardiology, Xijing Hospital, China; Center for Cardiovascular Research and Alternative Medicine, School of Pharmacy, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA. Electronic address: zhangym197951@126.com.
Xuefeng HanCenter for Cardiovascular Research and Alternative Medicine, School of Pharmacy, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA; Department of Physiology, Fourth Military Medical University, Xi'an 710032, China.
Nan HuCenter for Cardiovascular Research and Alternative Medicine, School of Pharmacy, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA.
Anna F HuffCenter for Cardiovascular Research and Alternative Medicine, School of Pharmacy, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA.
Feng GaoDepartment of Cardiology, Xijing Hospital, China; Department of Physiology, Fourth Military Medical University, Xi'an 710032, China.
Jun RenDepartment of Cardiology, Xijing Hospital, China; Center for Cardiovascular Research and Alternative Medicine, School of Pharmacy, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA. Electronic address: jren@uwyo.edu.
University of Wyoming · USAir Force Medical University · CN

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Nicolas A. Blouin · 2012 to 2026
$56.8M
Wyoming IDeA Networks of Biomedical Research ExcellenceP20RR016474 · NCRR · UNIVERSITY OF WYOMING · PI REN, JUN · 2001 to 2011
$28.2M
NCRR NIH HHS 5P20RR016474NCRR NIH HHS P20 RR016474NIGMS NIH HHS 8P20GM103432NIGMS NIH HHS P20 GM103432
6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). At the request of the University of Wyoming, this article has been retracted. Although an investigation report from Air Force Medical University found no evidence of misconduct, the University of Wyoming’s institutional investigation of the work authored by Dr. Jun Ren found evidence of data irregularities in Figures 2, 3, and 4 that affect the reported results and conclusions. All authors have been notified of the retraction of this article.

Indexed as

Caloric RestrictionAnimalsAutophagyAutophagy-Related Protein-1 HomologCalciumHeartMaleMiceMice, Inbred C57BLMice, KnockoutMyocardial ContractionMyocardiumMyocytes, CardiacPhosphorylationProtein Serine-Threonine KinasesProto-Oncogene Proteins c-aktAkt2 protein, mouseAutophagy-Related Protein-1 HomologCalciummTOR protein, mouseProtein Serine-Threonine KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesUlk1 protein, mouseAkt2AMPKAutophagyCaloric restrictionmTORMyocardial

Identifiers

PMID24368095
PMCPMC4076444
OpenAlexW2042827971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.