Evidence map›Paper›PMID 24368014›Full record

ReviewTissue engineering. Part B, Reviews2014

Establishing a bone marrow stromal cell transplant program at the National Institutes of Health Clinical Center.

David F Stroncek, Marianna Sabatino, Jiaqiang Ren, Lee England, Sergei A Kuznetsov, Harvey G Klein, Pamela G Robey

Abstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Simvastatin improves the homing of BMSCs via the PI3K/AKT/miR-9 pathway.Journal of cellular and molecular medicine · 2016
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David F Stroncek1 Department of Transfusion Medicine, Clinical Center, National Institutes of Health , Bethesda, Maryland.
Marianna Sabatino
Jiaqiang Ren
Lee England
Sergei A Kuznetsov
Harvey G Klein
Pamela G Robey
National Institutes of Health Clinical Center · USNational Institutes of Health · US

Funding

NIDCR DIR Production FacilitiesZIBDE000730 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI ROBEY, PAMELA G · 2009 to 2014
$1.2M
Development of novel cell and gene therapiesZIACL002120 · CLC · CLINICAL CENTER · PI STRONCEK, DAVID · 2009 to 2025
$0k
Intramural NIH HHS
6 · The paper itself

Abstract

A repository of cryopreserved bone marrow stromal cell (BMSC) products prepared from marrow aspirates of healthy subjects has been created and is being used to treat patients with inflammatory bowel disease, cardiovascular disease, and acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation. New methods of manufacturing BMSCs are being investigated including the use of an automated bioreactor for BMSC expansion and the replacement of fetal bovine serum with human platelet lysate as a media supplement. Efforts are also being made to identify markers that can be used to assess the potency of BMSCs.

Indexed as

Batch Cell Culture TechniquesMesenchymal Stem Cell TransplantationStem Cell ResearchAnimalsBiological Specimen BanksCells, CulturedGovernment ProgramsHumansMesenchymal Stem CellsNational Institutes of Health (U.S.)Tissue EngineeringUnited States

Identifiers

PMID24368014
PMCPMC4030651
OpenAlexW2064406318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.