ArticleParasites & vectors2013
Expression and accumulation of the two-domain odorant-binding protein AaegOBP45 in the ovaries of blood-fed Aedes aegypti.
Article in Parasites & vectors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Olfactory binding proteins: a review across the Insecta.Frontiers in zoology · 2025Review
- Article
- Identification of candidate chemosensory genes inFrontiers in physiology · 2024Article
- Expression and purification of Drosophila OBP44a with the aids of LC-MS and NMR.Protein expression and purification · 2023Article
- iOBPdb A Database for Experimentally Determined Functional Characterization of Insect Odorant Binding Proteins.Scientific data · 2023Article
- Identification of Odorant-Binding and Chemosensory Protein Genes inFrontiers in physiology · 2022Article
- Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster.Molecular biology and evolution · 2021Article
- The 40-Year Mystery of Insect Odorant-Binding Proteins.Biomolecules · 2021Review
- Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail.Scientific reports · 2020Article
- Odorant-Binding Proteins Contribute to the Defense of the Red Flour Beetle,Frontiers in physiology · 2020Article
- Transcriptome sequencing of Tessaratoma papillosa antennae to identify and analyze expression patterns of putative olfaction genes.Scientific reports · 2017Article
- Article
- Male tarsi specific odorant-binding proteins in the diving beetle Cybister japonicus sharp.Scientific reports · 2016Article
- The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction.Scientific reports · 2016Article
- Antennal and Abdominal Transcriptomes Reveal Chemosensory Genes in the Asian Citrus Psyllid, Diaphorina citri.PloS one · 2016Article
- Article
- Integrated proteomic and transcriptomic analysis of the Aedes aegypti eggshell.BMC developmental biology · 2014Article
- Soluble proteins of chemical communication: an overview across arthropods.Frontiers in physiology · 2014Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAedes aegypti mosquitoes are the main vectors of dengue viruses. Despite global efforts to reduce the prevalence of dengue using integrated vector management strategies, innovative alternatives are necessary to help prevent virus transmission. Detailed characterizations of Ae. aegypti genes and their products provide information about the biology of mosquitoes and may serve as foundations for the design of new vector control methods.
findingsWe studied the Ae. aegypti gene, AAEL010714, that encodes a two-domain odorant-binding protein, AaegOBP45. The predicted gene structure and sequence were validated, although single nucleotide polymorphisms were observed. Transcriptional and translational products accumulate in the ovaries of blood fed females and are not detected or are at low abundance in other tissues.
conclusionsWe validated the Ae. aegypti AAEL010714 gene sequence and characterized the expression profile of a two-domain OBP expressed in ovaries. We propose that AaegOBP45 function as a component of the mosquito eggshell.
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