ArticleMuscles, ligaments and tendons journal2013
Tissue-engineered augmentation of a rotator cuff tendon using a reconstituted collagen scaffold: a histological evaluation in sheep.
Article in Muscles, ligaments and tendons journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Resorbable Bio-Inductive Collagen Implant for Rotator Cuff Repair: What We Know, What We Need to Know, and the Path Forward.Orthopaedic surgery · 2025Pooled it
- The bioinductive collagen implant yields positive histological, clinical and MRI outcomes in the management of rotator cuff tears: A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Pooled it
- Article
- Histologic outcomes of rotator cuff patch augmentation: a literature review.JSES reviews, reports, and techniques · 2026Review
- Anterior Cruciate Ligament Repair: Surgical Technique Using Augmentation With Biocomposite Scaffold.Arthroscopy techniques · 2026Article
- Bioinductive scaffold augmentation of the patellar tendon: a scoping review of indications, techniques and early outcomes.International orthopaedics · 2026Article
- Promoting hematoma-like tissue formation in arthroscopic rotator cuff repair: impact of a bioinductive collagen implant.JSES international · 2026Article
- Bioinductive Collagen Augmentation in Arthroscopic Rotator Cuff Repair: 24-Month MRI and Clinical Outcomes.Journal of clinical medicine · 2026Article
- Structural integrity vs. clinical utility: a critical review of bio-inductive scaffolds and autologous alternatives in rotator cuff repair.Frontiers in medicine · 2026Review
- The role of new synthetic membranes in rotator cuff augmentation.Journal of experimental orthopaedics · 2026Review
- Arthroscopic Bioinductive Collagen Scaffold Augmentation in High-Risk Posterosuperior Rotator Cuff Tears: Clinical and Radiological Outcomes.Journal of clinical medicine · 2025Article
- Minimal Stiffness After Rotator Cuff Repair With Bioinductive Collagen Implants.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Long Head of the Biceps Tendon Augmentation Enhanced With a Bioinductive Collagen Patch for Massive and Retracted Rotator Cuff Tears.Arthroscopy techniques · 2025Article
- Bridging Reconstruction Using a Biocomposite Scaffold for Large/Massive Rotator Cuff Tears: A Technique Guide.Arthroscopy techniques · 2025Article
- Fat Expansion Not Fat Infiltration of Muscle Post Rotator Cuff Tendon Tears of the Shoulder: Regenerative Engineering Implications.Regenerative engineering and translational medicine · 2025Article
- The Clinical Application of Gel-Based Composite Scaffolds in Rotator Cuff Repair.Gels (Basel, Switzerland) · 2024Review
- Augmentation of triceps tendon repair with a bio-inductive collagen scaffold.BMJ case reports · 2023Article
- Revision Rotator Cuff Repair With Versus Without an Arthroscopically Inserted Onlay Bioinductive Implant in Workers' Compensation Patients.Orthopaedic journal of sports medicine · 2023Article
- Revision arthroscopic surgery after rotator cuff repair with a collagen graft: histologic evaluation of biopsy specimens from two patients.JSES reviews, reports, and techniques · 2022Article
- Rotator cuff repair using a bioresorbable nanofiber interposition scaffold: a biomechanical and histologic analysis in sheep.Journal of shoulder and elbow surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine if an absorbable collagen scaffold of high porosity would allow rapid tissue in-growth and permit the functional maturation and alignment of tendon-like tissue, scaffolds were sutured to the superficial surface of the infraspinatus tendons of adult sheep. Histology demonstrated complete ingrowth with fibrovascular tissue by 6 weeks and by 12 weeks the scaffold had induced the formation of a layer of dense, regularly-oriented collagenous tissue which significantly increased the thickness of the native tendon. This new tissue was well-integrated into the host tissues at both the bone interface and along the length of the tendon. At 26 weeks the scaffold was completely absorbed leaving a stable layer of mature tendon-like tissue over the surface of the host tendon which was still present at 52 weeks. The use of a reconstituted collagen scaffold consistently increased the thickness of a rotator cuff tendon by inducing the formation of a well-integrated and mature tendon-like tissue.
Indexed as
Identifiers
24367785PMC3838334W1576235996What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.