ArticleOxidative medicine and cellular longevity2013
Allergological and toxicological aspects in a multiple chemical sensitivity cohort.
Article in Oxidative medicine and cellular longevity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Italian Expert Consensus on Clinical and Therapeutic Management of Multiple Chemical Sensitivity (MCS).International journal of environmental research and public health · 2021Pooled it
- Multiple Chemical Sensitivity: an Italian prevalence multicentric survey.Frontiers in public health · 2025Article
- Prevalence and Factors Related to High Risk of Multiple Chemical Sensitivity among Japanese High School Students.International journal of environmental research and public health · 2024Article
- Volatile organic compounds (VOCs) in exhaled breath as a marker of hypoxia in multiple chemical sensitivity.Physiological reports · 2021Article
- Chemical Exposure, Risk of Multiple Chemical Sensitivity, and Occupational Safety.Safety and health at work · 2020Article
- T Cell Subpopulations in the Physiopathology of Fibromyalgia: Evidence and Perspectives.International journal of molecular sciences · 2020Review
- Prevalence and risk factors for multiple chemical sensitivity in Australia.Preventive medicine reports · 2019Article
- Increased Systemic Malondialdehyde Levels and Decreased Mo/Co, Co/FeJournal of clinical medicine · 2019Article
- Increased Mercury Levels in Patients with Celiac Disease following a Gluten-Free Regimen.Gastroenterology research and practice · 2015Article
- Article
- Repeated pulmonary exposures to zinc ions enhance inflammatory responses to subsequent metal exposures.Experimental lung researchArticle
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple chemical sensitivity (MCS) is a chronic condition characterized by an exaggerated response to toxicants. We ascertained the prevalence of allergy to metals and toxicological aspects in MCS patients.
methodsWe conducted a retrospective review of medical records of 41 patients with MCS. We performed patch testing (n = 21) for dental series and did lymphocyte transformation test (n = 18) for metals. We measured mercury in samples of blood (n = 19), urine (n = 19), saliva (n = 20), and scalp hair (n = 17) to investigate the association between mercury levels and cases of MCS.
resultsThe prevalence of metal immune hypersensitivity in a subset of 26 patients was 92.3 percent. Elevations of mercury occurred in 81.2 percent (26 of 32). The mean (±SD) in blood concentrations of mercury was 7.6 ± 13.6 μg/L; mean in urine was 1.9 ± 2.5 μg/L; mean in scalp hair was 2.2 ± 2.5 μg/g; mean in saliva was 38.1 ± 52.1 μg/L. Subgroup analyses showed that elevation of mercury levels in biological matrices were associated with mercury amalgams in patients with MCS (22 patients), compared with controls (8 patients) (odds ratio 11 : 95 percent confidence interval 1.5 to 81.6; P = 0.023).
conclusionsOur data show an increased prevalence of metal allergy and elevation of mercury levels in bioindicators among patients with MCS.
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