ReviewHepatic medicine : evidence and research2010
Optimal management of hepatorenal syndrome in patients with cirrhosis.
Review in Hepatic medicine : evidence and research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Albumin treatment regimen for type 1 hepatorenal syndrome: a dose-response meta-analysis.BMC gastroenterology · 2015Pooled it
- Extracorporeal liver support techniques: a comparison.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024Article
- [Hepatorenal Syndrome].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- Role of endotoxemia in causing renal dysfunction in cirrhosis.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020Review
- Does Anemia Have a Potential Effect on Type 2 Hepatorenal Syndrome?Canadian journal of gastroenterology & hepatology · 2020Article
- Development of a rat model of D-galactosamine/lipopolysaccharide induced hepatorenal syndrome.World journal of gastroenterology · 2015Article
- Treatment and management of ascites and hepatorenal syndrome: an update.Therapeutic advances in gastroenterology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatorenal syndrome (HRS) is a functional renal failure that often occurs in patients with cirrhosis and ascites. HRS develops as a consequence of a severe reduction of effective circulating volume due to both an extreme splanchnic arterial vasodilatation and a reduction of cardiac output. There are 2 different types of HRS. Type 1 HRS, which is often precipitated by a bacterial infection, especially spontaneous bacterial peritonitis, is characterized by a rapidly progressive impairment of renal function. Despite its functional origin, the prognosis of type 1 HRS is very poor. Type 2 HRS is characterized by a stable or slowly progressive renal failure so that its main clinical consequence is not acute renal failure but refractory ascites and its impact on prognosis is less negative. New treatments (vasoconstrictors plus albumin, transjugular portosystemic shunt, and molecular adsorbent recirculating system), which were introduced in the past 10 years, are effective in improving renal function in patients with HRS. Among these treatments vasoconstrictors plus albumin can also improve survival in patients with type 1 HRS. Thus, this therapeutic approach has changed the management of this severe complication in patients with advanced cirrhosis.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.