Evidence map›Paper›PMID 24367174›Full record

ArticleBreast cancer (Dove Medical Press)2011

Estrogen receptor (ER) and progesterone receptor (PgR) in breast cancer of Indian women.

Amit V Patil, Rahul S Bhamre, Rajeev Singhai, Mukund B Tayade, Vinayak W Patil

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Breast cancer (Dove Medical Press), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amit V PatilDepartment of General Surgery, Government Medical College, Miraj, Maharashtra, India.
Rahul S BhamreDepartment of General Surgery, DY Patil Hospital and Research Centre, Nerul, Navi Mumbai, India.
Rajeev SinghaiDepartment of Biochemistry, Grant Medical College and Sir JJ Group of Hospitals Mumbai, India.
Mukund B TayadeDepartment of General Surgery, Grant Medical College and Sir JJ Group of Hospitals Mumbai, India.
Vinayak W PatilDepartment of Biochemistry, Grant Medical College and Sir JJ Group of Hospitals Mumbai, India.
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the expressions and relationship between estrogen receptors (ERs) and progesterone receptors (PgRs) in breast cancer in Indian women.

participantsSurgically removed breast cancer tissues were collected from Grant Medical College and Sir JJ Group of Hospitals, Mumbai, India, taking (n = 300) cases of infiltrating duct cancer of Indian women after radical mastectomy and lumpectomy; the age- and menopausal-related subgroups satisfied this requirement. MEASUREMENTS: Statistical significance was calculated by the likelihood ratio test; relative risk served to check for significant differences. Relapse-free interval probabilities were calculated according to Kaplan and Meier, with Cox-Mantel test comparing survival functions and P values.

resultsWe observed that only in middle-aged postmenopausal patients bearing pT2 tumors were ER and PgR receptors shown to have a prognostic significance with the lowest tested cutoff value being 5 fmol/mg.

conclusionImmunohistochemistry analysis has been shown to be a prognostic factor for patients with breast cancer; the major aim of determining the ER receptor status is to assess predictive response to hormonal therapy.

Indexed as

hormone receptorsimmunohistochemistryprognostic cancer tissue biomarkerssteroid receptors

Identifiers

PMID24367174
PMCPMC3846641
OpenAlexW2038140016

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.