Evidence map›Paper›PMID 24366906›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2015

Stability and plasticity of auditory brainstem function across the lifespan.

Erika Skoe, Jennifer Krizman, Samira Anderson, Nina Kraus

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07730710 (The Effect of Neuromotor-Cognitive Training on Dynamic Balance, Reaction Time and Sensorimotor Performance in Performance Dancers), which is not on this map. Cited by 97 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07730710 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Neuromotor-Cognitive Training on Dynamic Balance, Reaction Time and Sensorimotor Performance in Performance Dancers

TypeinterventionalSponsorYeditepe UniversityRan2026 to 2026Enrolled50ConditionsPostural Balance, Reaction Time, Sensorimotor Performance, Neuromuscular ControlArmsNeuromotor-Cognitive Training
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 3 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Pooled it
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  3. Click-evoked auditory brainstem responses and autism spectrum disorder: A meta-analytic review.Autism research : official journal of the International Society for Autism Research · 2018
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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Erika SkoeAuditory Neuroscience Laboratory Department of Communication Sciences Northwestern University, Evanston, IL 60208, USA Current address: Department of Speech, Language and Hearing Sciences, Faculty Affiliate of the Department of Psychology, Faculty Affiliate of the Cognitive Sciences Program, University of Connecticut, Storrs, CT 06269, USA.
Jennifer KrizmanAuditory Neuroscience Laboratory Department of Communication Sciences Bilingualism and Psycholinguistics Research Group Northwestern University, Evanston, IL 60208, USA.
Samira AndersonAuditory Neuroscience Laboratory Department of Communication Sciences Northwestern University, Evanston, IL 60208, USA Current address: Department of Hearing and Speech Science, University of Maryland, College Park, MD 20742, USA.
Nina KrausAuditory Neuroscience Laboratory Department of Communication Sciences Institute for Neuroscience Department of Neurobiology and Physiology Department of Otolaryngology Northwestern University, Evanston, IL 60208, USA.
Northwestern University · USUniversity of Maryland, College Park · US

Funding

A preschool biomarker for literacyR01HD069414 · NICHD · NORTHWESTERN UNIVERSITY · PI KRAUS, NINA · 2012 to 2016
$1.8M
Neural correlates of auditory function and training in older adultsR01DC010016 · NIDCD · NORTHWESTERN UNIVERSITY · PI DHAR, SUMITRAJIT, KRAUS, NINA · 2010 to 2014
$1.7M
NICHD NIH HHS R01 HD069414NIDCD NIH HHS R01 DC010016NIDCD NIH HHS R01 DC10016
6 · The paper itself

Abstract

The human auditory brainstem is thought to undergo rapid developmental changes early in life until age ∼2 followed by prolonged stability until aging-related changes emerge. However, earlier work on brainstem development was limited by sparse sampling across the lifespan and/or averaging across children and adults. Using a larger dataset than past investigations, we aimed to trace more subtle variations in auditory brainstem function that occur normally from infancy into the eighth decade of life. To do so, we recorded auditory brainstem responses (ABRs) to a click stimulus and a speech syllable (da) in 586 normal-hearing healthy individuals. Although each set of ABR measures (latency, frequency encoding, response consistency, nonstimulus activity) has a distinct developmental profile, across all measures developmental changes were found to continue well past age 2. In addition to an elongated developmental trajectory and evidence for multiple auditory developmental processes, we revealed a period of overshoot during childhood (5-11 years old) for latency and amplitude measures, when the latencies are earlier and the amplitudes are greater than the adult value. Our data also provide insight into the capacity for experience-dependent auditory plasticity at different stages in life and underscore the importance of using age-specific norms in clinical and experimental applications.

Indexed as

SpeechAcoustic StimulationAdolescentAdultAgedAge FactorsAgingBrain StemChildChild, PreschoolElectroencephalographyEvoked Potentials, Auditory, Brain StemFemaleHumansInfantMaleauditoryauditory brainstem responsedevelopment

Identifiers

PMID24366906
PMCPMC4428291
OpenAlexW2151886218

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.