Evidence map›Paper›PMID 24366690›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2014

Are short telomeres hallmarks of cancer recurrence?

Jerry W Shay

Open access · bronzeAbstract readComment
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Stress and telomere shortening among central Indian conservation refugees.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jerry W ShayAuthor's Affiliation: Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas.
The University of Texas Southwestern Medical Center · US

Funding

UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HEYMACH, JOHN V. · 1996 to 2024
$57.4M
UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Sandi Leigh Pruitt · 2010 to 2026
$53.7M
Cell Biology Research Improvements and RenovationsC06RR030414 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI FITZ, JOHN GREGORY · 2010 to 2010
$15.0M
Cancer Biology Training GrantT32CA124334 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAY, JERRY WILLIAM · 2007 to 2021
$5.3M
The Role of Telomeres and Telomerase in CancerR13CA113094 · NCI · AMERICAN ASSOCIATION FOR CANCER RESEARCH · PI SHAY, JERRY WILLIAM · 2005 to 2005
$5k
NCI NIH HHS 5P30CA 142543NCI NIH HHS P30 CA142543NCI NIH HHS P50 CA070907NCI NIH HHS R13 CA113094NCI NIH HHS T32 CA124334NCRR NIH HHS C06 RR030414NCRR NIH HHS C06 RR30414
6 · The paper itself

Abstract

Exposure to radiation and some chemotherapeutic agents is associated with an increased risk of developing second cancers. Short telomeres are almost universally associated with malignant cancer progression. An unanswered question is whether inherited short telomeres or therapy-related telomere shortening is a biomarker of the development of second malignant neoplasms.

Indexed as

FemaleHodgkin DiseaseHumansMaleNeoplasms, Second PrimaryTelomereThyroid Neoplasms

Identifiers

PMID24366690
PMCPMC3944321
OpenAlexW2050614435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.