Evidence map›Paper›PMID 24366648›Full record

ReviewJournal of neurology2014

Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations.

Seema Kalra, Alan Silman, Gulsen Akman-Demir, Saeed Bohlega, Afshin Borhani-Haghighi, Cris S Constantinescu, Habib Houman, Alfred Mahr, Carlos Salvarani, Petros P Sfikakis and 2 more

Open access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in Journal of neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 8 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 8 syntheses or guidelines pooled it, 328 citations in OpenAlex.

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  9. Article
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  12. Observational
  13. Article
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  15. Treat-to-target in Behçet syndrome.Nature reviews. Rheumatology · 2026
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Neuro-behcet's syndrome: epidemiology, mechanisms, and emerging strategies in diagnosis and treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 7 countries.

Seema KalraNeurology Research Department, University Hospital of North Staffordshire, Stoke-on-Trent, England, UK.
Alan Silman
Gulsen Akman-Demir
Saeed Bohlega
Afshin Borhani-Haghighi
Cris S Constantinescu
Habib Houman
Alfred Mahr
Carlos Salvarani
Petros P Sfikakis
Aksel Siva
Adnan Al-Araji
Royal Stoke University Hospital · GBFaculté de médecine de TunisIstanbul Bilim University · TRIstanbul University · TRIstituti di Ricovero e Cura a Carattere Scientifico · ITKing Faisal Specialist Hospital & Research Centre · SAShiraz University of Medical Sciences · IRUniversité Paris Cité · FRUniversity of Manchester · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease (BD), which is a relapsing inflammatory multisystem disease with an interesting epidemiology. Though NBD is relatively uncommon, being potentially treatable, neurologists need to consider it in the differential diagnosis of inflammatory, infective, or demyelinating CNS disorders. Evidence-based information on key issues of NBD diagnosis and management is scarce, and planning for such studies is challenging. We therefore initiated this project to develop expert consensus recommendations that might be helpful to neurologists and other clinicians, created through an extensive literature review and wide consultations with an international advisory panel, followed by a Delphi exercise. We agreed on consensus criteria for the diagnosis of NBD with two levels of certainty in addition to recommendations on when to consider NBD in a neurological patient, and on the use of various paraclinical tests. The management recommendations included treatment of the parenchymal NBD and cerebral venous thrombosis, the use of disease modifying therapies, prognostic factors, outcome measures, and headache in BD. Future studies are needed to validate the proposed criteria and provide evidence-based treatments.

Indexed as

Behcet SyndromeDiagnosis, DifferentialEvidence-Based PracticeHumansIntracranial ThrombosisVenous Thrombosis

Identifiers

PMID24366648
PMCPMC4155170
OpenAlexW1979534455

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.