SynthesisPediatric research2013
Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010.
Synthesis in Pediatric research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 391 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
391 citing papers in PubMed, 9 syntheses or guidelines pooled it, 784 citations in OpenAlex.
- Insulin-like growth factor-1 for the prevention or treatment of retinopathy of prematurity.The Cochrane database of systematic reviews · 2026Pooled it
- Prevalence and associated factors of retinopathy of prematurity in sub‑Saharan Africa: a systematic review and meta‑analysis.BMC ophthalmology · 2025Pooled it
- Significance of serum biomarkers in preterm infants screened for retinopathy of prematurity: a systematic review and meta-analysis.Eye (London, England) · 2025Pooled it
- Artificial intelligence-based algorithms for the diagnosis of retinopathy of prematurity.The Cochrane database of systematic reviews · 2025Pooled it
- Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled rials.BMJ open ophthalmology · 2024Pooled it
- Biomarkers in retinopathy of prematurity: a systematic review and meta-analysis.Frontiers in pediatrics · 2024Pooled it
- A Meta-Analysis of Neurodevelopmental Outcomes following Intravitreal Bevacizumab for the Treatment of Retinopathy of Prematurity.Neonatology · 2023Pooled it
- Costs associated with retinopathy of prematurity: a systematic review and meta-analysis.BMJ open · 2022Pooled it
- Effect of ranibizumab on retinopathy of prematurity: A meta-analysis.Frontiers in pharmacology · 2022Pooled it
- Platelet characteristics in extremely preterm infants after fatty acid supplementation: a randomized controlled trial.Pediatric research · 2025Trial
- Safety and efficacy of ripasudil eye drops in preterm infants with retinopathy of prematurity: phase 1/2, open label, single-arm trial.Japanese journal of ophthalmology · 2024Trial
- Low dose or very low dose phenylephrine and cyclopentolate microdrops for retinopathy of prematurity eye examinations (The Little Eye Drop Study): a randomised controlled non-inferiority trial.Archives of disease in childhood. Fetal and neonatal edition · 2023Trial
- Trial
- Comparison of clinical outcomes of conbercept versus ranibizumab treatment for retinopathy of prematurity: a multicentral prospective randomised controlled trial.The British journal of ophthalmology · 2022Trial
- Ranibizumab in retinopathy of prematurity - one-year follow-up of ophthalmic outcomes and two-year follow-up of neurodevelopmental outcomes from the CARE-ROP study.Acta ophthalmologica · 2022Trial
- Correlation between hyperglycemia and glycated albumin with retinopathy of prematurity.Scientific reports · 2021Trial
- Cost-Effectiveness of Telemedicine-Based Screening Programs for Retinopathy of Prematurity in Low- and Middle-Income Countries.Ophthalmology science · 2026Article
- Comparison of Two AI Chatbots for Diagnosis and Providing Treatment Suggestions in Retinopathy of Prematurity: Retrospective Study.Journal of medical Internet research · 2026Article
- Incidence and risk factors for retinopathy of prematurity: A hospital-based study in Iran.Eye (London, England) · 2026Article
- Frequency-specific gyro-sulcal functional differentiation in preterm neonates: Sulcal dominance and gene expression correlates.Developmental cognitive neuroscience · 2026Article
331 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRetinopathy of prematurity (ROP) is a leading cause of potentially avoidable childhood blindness worldwide. We estimated ROP burden at the global and regional levels to inform screening and treatment programs, research, and data priorities.
methodsSystematic reviews and meta-analyses were undertaken to estimate the risk of ROP and subsequent visual impairment for surviving preterm babies by level of neonatal care, access to ROP screening, and treatment. A compartmental model was used to estimate ROP cases and numbers of visually impaired survivors.
resultsIn 2010, an estimated 184,700 (uncertainty range: 169,600-214,500) preterm babies developed any stage of ROP, 20,000 (15,500-27,200) of whom became blind or severely visually impaired from ROP, and a further 12,300 (8,300-18,400) developed mild/moderate visual impairment. Sixty-five percent of those visually impaired from ROP were born in middle-income regions; 6.2% (4.3-8.9%) of all ROP visually impaired infants were born at >32-wk gestation. Visual impairment from other conditions associated with preterm birth will affect larger numbers of survivors.
conclusionImproved care, including oxygen delivery and monitoring, for preterm babies in all facility settings would reduce the number of babies affected with ROP. Improved data tracking and coverage of locally adapted screening/treatment programs are urgently required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.