Evidence map›Paper›PMID 24366132›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2014

How to build a grid cell.

Christoph Schmidt-Hieber, Michael Häusser

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Entorhinal Neurons Exhibit Cue Locking in Rodent VR.Frontiers in cellular neuroscience · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Space in the brain: how the hippocampal formation supports spatial cognition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christoph Schmidt-HieberWolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, , Gower Street, London WC1E 6BT, UK.
Michael Häusser

Funding

Wellcome Trust 094077
6 · The paper itself

Abstract

Neurons in the medial entorhinal cortex fire action potentials at regular spatial intervals, creating a striking grid-like pattern of spike rates spanning the whole environment of a navigating animal. This remarkable spatial code may represent a neural map for path integration. Recent advances using patch-clamp recordings from entorhinal cortex neurons in vitro and in vivo have revealed how the microcircuitry in the medial entorhinal cortex may contribute to grid cell firing patterns, and how grid cells may transform synaptic inputs into spike output during firing field crossings. These new findings provide key insights into the ingredients necessary to build a grid cell.

Indexed as

Models, NeurologicalAction PotentialsAnimalsEntorhinal CortexMiceNeuronsPatch-Clamp TechniquesSpatial Behaviorentorhinal cortexgrid cellneural circuitpatch clamppath integrationspatial navigation

Identifiers

PMID24366132
PMCPMC3866442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.