Evidence map›Paper›PMID 24366073›Full record

ReviewNature reviews. Cardiology2014

Treatment of refractory angina in patients not suitable for revascularization.

Timothy D Henry, Daniel Satran, E Marc Jolicoeur

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03991871 (HARapan kiTa ECP), which is not on this map. Cited by 54 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 5 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03991871 naunknown statusnot on this mapstarted 2019, after this paper: background citation

HARapan kiTa ECP (External Counter Pulsation) Study HARTEC Study

TypeinterventionalSponsorNational Cardiovascular Center Harapan Kita Hospital IndonesiaRan2019 to 2020Enrolled50ConditionsCardiac Rehabilitation, Angiogenesis, Refractory AnginaArmsExternal Counter Pulsation (ECP) therapy
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 5 syntheses or guidelines pooled it, 140 citations in OpenAlex.

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  20. Contemporary Management of Refractory Angina.Interventional cardiology clinics · 2022
    Review
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Timothy D HenryCedars-Sinai Heart Institute, 127 South San Vicente Boulevard, AHSP, A3100, Los Angeles, CA 90048, USA.
Daniel SatranPark Nicollet Heart and Vascular Center, 6500 Excelsior Boulevard, St Louis Park, MN 55426, USA.
E Marc JolicoeurDepartment of Medicine, Montreal Heart Institute, Université de Montréal, 5000 Belanger East Street, Montreal, Québec H1T 1C8, Canada.
Cedars-Sinai Medical Center · USMontreal Heart Institute · CAPark Nicollet Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A growing number of patients, particularly those with advanced, chronic coronary artery disease, experience symptoms of angina that are refractory to treatment with β-blockers, calcium-channel blockers, and long-acting nitrates, despite revascularization. The management of patients with refractory angina who are unsuitable for further revascularization is strikingly different across the world, and is contingent on local resources and available expertise. Mortality in this patient population has decreased, but enhancing quality of life remains a challenge. New treatment principles are emerging in current practice, such as metabolic modulation, therapeutic angiogenesis, and novel interventional techniques (coronary in-flow redistribution and approaches to chronic total occlusion). The contemporary management of refractory angina encourages individualized, patient-centred care in interdisciplinary, specialized clinics. Global initiatives are required to address complex clinical problem-solving for patients with refractory angina. In this Review, we discuss the epidemiology of refractory angina, and provide an update on the pharmacological, noninvasive, and interventional options that are available to these patients or are under development.

Indexed as

Myocardial RevascularizationAngina PectorisContraindicationsDiagnostic ImagingFibrinolytic AgentsHumansSeverity of Illness IndexThrombolytic TherapyTreatment OutcomeFibrinolytic Agents

Identifiers

PMID24366073
OpenAlexW1988592291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.