ArticlePsychology and aging2013
Cognitive activities and cognitive performance in middle-aged adults at risk for Alzheimer's disease.
Article in Psychology and aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 65 citations in OpenAlex.
- Ceramides may Play a Central Role in the Pathogenesis of Alzheimer's Disease: a Review of Evidence and Horizons for Discovery.Molecular neurobiology · 2025Review
- Lifestyle, genetic risk, plasma pTau217, and incident cognitive impairment in WRAP.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Combination of Physical Activity and Cognitive Games is Associated With Better Cognitive Performance and Gray Matter Volume in Older Adults.International journal of geriatric psychiatry · 2025Article
- Self-reported mid- to late-life physical and recreational activities: Associations with late-life cognition.Journal of the International Neuropsychological Society : JINS · 2024Article
- Empirically derived psychosocial-behavioral phenotypes in Black/African American and Hispanic/Latino older adults enrolled in HABS-HD: Associations with AD biomarkers and cognitive outcomes.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Social support and cognitive activity and their associations with incident cognitive impairment in cognitively normal older adults.BMC geriatrics · 2024Article
- The Effects of Occupational Complexity on Late Life Cognition in ACTIVE: Examining the Mediating and Moderating Effects of Race.Journal of aging and health · 2023Article
- The relationship between cognitive engagement and better memory in midlife.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Quantitative MRI Evidence for Cognitive Reserve in Healthy Elders and Prodromal Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2022Article
- Factors Associated With Dementia Knowledge and Dementia Worry in the South Korean Elderly Population.Psychiatry investigation · 2021Article
- Influence of mid-life cognitive activity on cognitive function among men aged 68 years or older.Aging clinical and experimental research · 2021Article
- The longitudinal association between social network composition and episodic memory in older adulthood: the importance of contact frequency with friends.Aging & mental health · 2020Article
- Cognitive Diversity in a Healthy Aging Cohort: Cross-Domain Cognition in the Cam-CAN Project.Journal of aging and health · 2020Article
- Longitudinal Associations Between Contact Frequency with Friends and with Family, Activity Engagement, and Cognitive Functioning.Journal of the International Neuropsychological Society : JINS · 2020Article
- Linking depressive symptoms and cognitive functioning: The mediating role of leisure activity.Neuropsychology · 2020Article
- Late-Life Physical and Cognitive Activities Independently Contribute to Brain and Cognitive Resilience.Journal of Alzheimer's disease : JAD · 2020Article
- Social network characteristics and cognitive functioning in ethnically diverse older adults: The role of network size and composition.Neuropsychology · 2019Article
- Social relations and age-related change in memory.Psychology and aging · 2019Article
- Association of longitudinal white matter degeneration and cerebrospinal fluid biomarkers of neurodegeneration, inflammation and Alzheimer's disease in late-middle-aged adults.Brain imaging and behavior · 2019Observational
- Occupational cognitive complexity in earlier adulthood is associated with brain structure and cognitive health in midlife: The CARDIA study.Neuropsychology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Cognitive activity is thought to provide some protection against dementia, but the mechanism and timing of these effects are unknown. Data for this study were drawn from the Wisconsin Registry for Alzheimer's Prevention (WRAP), an at-risk middle-aged sample (mean age = 54 years) enriched for parental family history of Alzheimer's disease (AD). We had two main aims: (a) to determine the relative contribution of three facets of cognitive activity-education, occupational complexity with data, and cognitive leisure activities-to WRAP participants' cognitive performance; and (b) to assess for interactions between genetic risk factors and cognitive activity in explaining cognitive performance. Results from mixed effects models indicate that some of the variance usually attributed to education may be more closely accounted for by cognitive activities later in life. Overall, our analyses suggest cautious optimism for cognitive activities, especially game playing, as a strategy for preserving cognitive strengths in midlife.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.