ArticleBrain and behavior2013
Blood pressure fluctuation and hypertension in patients with Parkinson's disease.
Article in Brain and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Management of Hypertension and Blood Pressure Dysregulation in Patients with Parkinson's Disease-a Systematic Review.Current hypertension reports · 2021Pooled it
- Sympathetic Shift and Insular Alteration: Unravelling the Link Between Anxiety and Heart Rate Variability in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- The impact of short-term blood pressure variability on cognitive decline in Parkinson's disease patients without co-morbidities.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Blood Pressure Variability as a Diagnostic Marker for α-Synucleinopathy in Patients With Orthostasis.Journal of the American Heart Association · 2025Article
- Advice to people with Parkinson's in my clinic: Get a cardiopulmonary exercise test.Journal of Parkinson's disease · 2025Article
- Autonomic dysfunction in neurodegenerative disease.Nature reviews. Neuroscience · 2025Review
- Is practitioner appraisal of facial expressivity and emotional engagement in simulated Parkinson's disease affected by race?Clinical parkinsonism & related disorders · 2025Article
- Molecular characterization of the circadian clock in patients with Parkinson's disease-CLOCK4PD Study protocol.PloS one · 2024Article
- Chaudhuri's Dashboard of Vitals in Parkinson's syndrome: an unmet need underpinned by real life clinical tests.Frontiers in neurology · 2023Review
- Sleep and circadian rhythms in Parkinson's disease and preclinical models.Molecular neurodegeneration · 2022Review
- Photobiomodulation for Hypertension and Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2022Review
- 24-hour ambulatory blood pressure alterations in patients with Parkinson's disease.Brain and behavior · 2022Article
- Tooth Loss and Blood Pressure in Parkinson's Disease Patients: An Exploratory Study on NHANES Data.International journal of environmental research and public health · 2021Article
- Progression of Nonmotor Symptoms in Parkinson's Disease by Sex and Motor Laterality.Parkinson's disease · 2021Article
- Linking chronic kidney disease and Parkinson's disease: a literature review.Metabolic brain disease · 2021Review
- Hypertension, Antihypertensive Use and the Delayed-Onset of Huntington's Disease.Movement disorders : official journal of the Movement Disorder Society · 2020Observational
- Gut microbiota and neuroinflammation in pathogenesis of hypertension: A potential role for hydrogen sulfide.Pharmacological research · 2020Review
- Acupuncture Treatment Reduces Incidence of Parkinson's Disease in Patients With Depression: A Population-Based Retrospective Cohort Study in Taiwan.Frontiers in aging neuroscience · 2020Article
- Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back.International journal of molecular sciences · 2018Review
- Hypertension and Diagnosis of Parkinson's Disease: A Meta-Analysis of Cohort Studies.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesBlood pressure (BP) abnormalities have been known in Parkinson's disease (PD) patients. The present study aimed at determining how the BPs of PD patients fluctuate in a day.
methodsA total of 37 PD patients and 44 OD (other disease) patients, all of who were inpatients, were monitored every 30 min by 24-h ambulatory blood pressure monitoring (ABPM).
resultsThe average systolic BP and the number of patients who showed postprandial hypotension were not different between the two groups. However, occurrence of nocturnal hypertension, BP fluctuation of over 100 mmHg in a day and BP of over 200 mmHg were significantly more frequently observed in the PD patients than in the OD patients. In the PD patients, these parameters were not different between those who were suffering from the disease for less than 10 years and those with the disease for 10 years or longer, as well as between those who had a Hoehn-Yahr staging scale of 2-3 and those with a scale of 4-5.
conclusionTwenty-four-hour ABPM, not BP measurement once a day, enables us to determine the actual BP in PD patients. Although hypotension is a severe risk factor for falling and syncope, we emphasize the importance of monitoring rather hypertension and fluctuating BP in PD patients that may lead to a variety of other undesirable conditions. Management of hypotension, hypertension, and BP fluctuation is an important issue in the future.
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