ReviewInternational journal of endocrinology2013
Sperm proteomics: road to male fertility and contraception.
Review in International journal of endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 96 citations in OpenAlex.
- Gestational benzyl butyl phthalate exposure impairs sperm capacitation in F1 offspring by altering PKA-associated signaling and tyrosine phosphorylation.Archives of toxicology · 2026Article
- N-myristoyltransferase 1, a key gene for protein N-myristoylation, is dispensable for fertility in male mice.The Journal of reproduction and development · 2026Article
- Sperm capacitation ability, as evaluated by Cap-Score™, has little impact on ICSI success.Journal of assisted reproduction and genetics · 2026Article
- Comprehensive proteomics analysis of bovine sperm head plasma membrane associated with fertility.Scientific reports · 2026Article
- Differential protein repertoires related to sperm function identified in extracellular vesicles (EVs) in seminal plasma of distinct fertility buffalo (Frontiers in cell and developmental biology · 2024Article
- The proteomic landscape of sperm surface deciphers its maturational and functional aspects in buffalo.Frontiers in physiology · 2024Article
- Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.Frontiers in reproductive health · 2024Article
- Identification of protein candidates in spermatozoa of water buffalo (Frontiers in cell and developmental biology · 2023Article
- Characterization of the Testis-Specific Angiotensin Converting Enzyme (tACE)-Interactome during Bovine Sperm Capacitation.Current issues in molecular biology · 2022Article
- Influence of Risk Factors for Male Infertility on Sperm Protein Composition.International journal of molecular sciences · 2021Review
- Current markers for infertility in men.JBRA assisted reproduction · 2021Article
- Effect of adding different concentrations of L-arginine to Tris-yolk extender on the quality of sub-fertile ejaculates in buffalo.Tropical animal health and production · 2021Article
- Article
- Comparative Proteomic Analysis of Proteins Involved in Bioenergetics Pathways Associated with Human Sperm Motility.International journal of molecular sciences · 2019Article
- Proteomic Changes in Human Sperm During SequentialFrontiers in cell and developmental biology · 2019Article
- New Biological Insights on X and Y Chromosome-Bearing Spermatozoa.Frontiers in cell and developmental biology · 2019Review
- Expression pattern of prohibitin, capping actin protein of muscle Z-line beta subunit and tektin-2 gene in Murrah buffalo sperm and its relationship with sperm motility.Asian-Australasian journal of animal sciences · 2018Article
- Comparative Proteomics Reveal the Association between SPANX Proteins and Clinical Outcomes of Artificial Insemination with Donor Sperm.Scientific reports · 2018Article
- Low doses of chlorpyrifos interfere with spermatogenesis of rats through reduction of sex hormones.Environmental science and pollution research international · 2017Article
- Male caffeine and alcohol intake in relation to semen parameters and in vitro fertilization outcomes among fertility patients.Andrology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis. In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very suitable for proteomic studies. Recently, the application of proteomic approaches such as the two-dimensional polyacrylamide gel electrophoresis, mass spectrometry, and differential in-gel electrophoresis has identified several sperm-specific proteins. These findings have provided a further understanding of protein functions involved in different sperm processes as well as of the differentiation of normal state from an abnormal one. In addition, studies on the sperm proteome have demonstrated the importance of spermatozoal posttranslational modifications and their ability to induce physiological changes responsible for fertilization. Large-scale proteomic studies to identify hundreds to thousands of sperm proteins will ultimately result in the development of novel biomarkers that may help to detect fertility, the state of complete contraception, and beyond. Eventually, these protein biomarkers will allow for a better diagnosis of sperm dysfunctions and aid in drug development. This paper reviews the recent scientific publications available from the PubMed database to address sperm proteomics and its potential application to characterize male fertility and contraception.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.