ArticleCurrent organic chemistry2013
Dual Functional Small Molecule Probes as Fluorophore and Ligand for Misfolding Proteins.
Article in Current organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 29 citations in OpenAlex.
- Ligands for Protein Fibrils of Amyloid-β, α-Synuclein, and Tau.Chemical reviews · 2025Review
- In vivo three-dimensional brain imaging with chemiluminescence probes in Alzheimer's disease models.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Differentiating Aβ40 and Aβ42 in amyloid plaques with a small molecule fluorescence probe.Chemical science · 2020Article
- To What Extent Are the Terminal Stages of Sepsis, Septic Shock, Systemic Inflammatory Response Syndrome, and Multiple Organ Dysfunction Syndrome Actually Driven by a Prion/Amyloid Form of Fibrin?Seminars in thrombosis and hemostasis · 2018Review
- Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker™ stains.Journal of the Royal Society, Interface · 2018Article
- Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species.Chemical science · 2017Article
- Design and synthesis of a fluorescent probe based on naphthalene anhydride and its detection of copper ions.PloS one · 2017Article
- Advances in development of fluorescent probes for detecting amyloid-β aggregates.Acta pharmacologica Sinica · 2016Review
- Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer׳s disease.Acta pharmaceutica Sinica. B · 2015Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Misfolding of a protein is a destructive process for variety of diseases that include neurodegenerative diseases such as Alzheimer's disease, Parkinson disease, Huntington disease, mad cow disease, amyotrophic lateral sclerosis (ALS), and frontal temporal dementia (FTD), and other non-CNS diseases such as diabetes, cystic fibrosis, and lysosomal storage diseases. Formation of various misfunctional large assembles of the misfolded protein is the primary consequence. To detect the formation of the aggregated species is very important for not only basic mechanism research but also very crucial for diagnosis of the diseases. In this review, we updated references related to the new development of the dual functional fluorescent small molecule probes for detecting the aggregated proteins
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