ArticleNew journal of physics2013
Collective cell streams in epithelial monolayers depend on cell adhesion.
Article in New journal of physics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 49 citations in OpenAlex.
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- Mathematical model for promotion of wound closure with ATP release.Biophysics and physicobiology · 2023Article
- Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction.Frontiers in cell and developmental biology · 2022Article
- Viscoelasticity, Like Forces, Plays a Role in Mechanotransduction.Frontiers in cell and developmental biology · 2022Review
- In-frame deletion of SPECC1L microtubule association domain results in gain-of-function phenotypes affecting embryonic tissue movement and fusion events.Human molecular genetics · 2021Article
- Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes.Journal of visualized experiments : JoVE · 2021Article
- SPECC1L-deficient primary mouse embryonic palatal mesenchyme cells show speed and directionality defects.Scientific reports · 2021Article
- In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition.Nature communications · 2020Article
- Automated Design of Pluripotent Stem Cell Self-Organization.Cell systems · 2019Article
- Adjustable viscoelasticity allows for efficient collective cell migration.Seminars in cell & developmental biology · 2019Review
- Neural crest streaming as an emergent property of tissue interactions during morphogenesis.PLoS computational biology · 2019Article
- Senescent tumor cells building three-dimensional tumor clusters.Scientific reports · 2018Article
- Physical models of collective cell motility: from cell to tissue.Journal of physics D: Applied physics · 2017Article
- Modeling cell shape and dynamics on micropatterns.Cell adhesion & migration · 2016Article
- In vivo confinement promotes collective migration of neural crest cells.The Journal of cell biology · 2016Article
- Spatio-temporal morphology changes in and quenching effects on the 2D spreading dynamics of cell colonies in both plain and methylcellulose-containing culture media.Journal of biological physics · 2016Article
- The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development.Developmental cell · 2016Article
- Dynamics of Cell Ensembles on Adhesive Micropatterns: Bridging the Gap between Single Cell Spreading and Collective Cell Migration.PLoS computational biology · 2016Article
- Coherent Motion of Monolayer Sheets under Confinement and Its Pathological Implications.PLoS computational biology · 2015Article
- Collisions of deformable cells lead to collective migration.Scientific reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
We report a spontaneously emerging, randomly oriented, collective streaming behavior within a monolayer culture of a human keratinocyte cell line, and explore the effect of modulating cell adhesions by perturbing the function of calcium-dependent cell adhesion molecules. We demonstrate that decreasing cell adhesion induces narrower and more anisotropic cell streams, reminiscent of decreasing the Taylor scale of turbulent liquids. To explain our empirical findings, we propose a cell-based model that represents the dual nature of cell-cell adhesions. Spring-like connections provide mechanical stability, while a cellular Potts model formalism represents surface-tension driven attachment. By changing the relevance and persistence of mechanical links between cells, we are able to explain the experimentally observed changes in emergent flow patterns.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.