SynthesisWorld journal of gastroenterology2013
Bile leakage test in liver resection: a systematic review and meta-analysis.
Synthesis in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The E-AHPBA-ESSO-Innsbruck consensus recommendations on peri- and postoperative management following liver resection.The British journal of surgery · 2025Guideline
- Terlipressin in the treatment of hepatorenal syndrome: A systematic review and meta-analysis.Medicine · 2018Pooled it
- Routine White test for earlyBMJ open · 2026Article
- A novel bile leak test using contrast-enhanced intraoperative ultrasonic cholangiography in liver resection: a prospective single-arm trial.Surgical endoscopy · 2026Article
- Article
- Simultaneous combined surgery for hepatic-renal double organ alveolar or cystic echinococcosis: A retrospective study.World journal of gastrointestinal surgery · 2025Article
- Efficacy of preoperative endoscopic nasobiliary drainage tube placement for liver cancer adjacent to the hepatic hilum.Langenbeck's archives of surgery · 2025Article
- STANDARDIZATION OF THE WHITE TEST IN OPEN LIVER RESECTION: TOWARD NEAR-ZERO CLINICALLY SIGNIFICANT BILE LEAKAGE.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Article
- Current applications of indocyanine green (ICG) in abdominal, gynecologic and urologic surgery: a meta-review and quality analysis with use of the AMSTAR 2 instrument.Surgical endoscopy · 2024Review
- Risk factors and management of biliary leakage after Endocystectomy for hepatic cystic echinococcosis.PLoS neglected tropical diseases · 2023Article
- Laparoscopic left hemihepatectomy guided by real-time indocyanine green fluorescence imaging using the arantius-first approach.World journal of surgical oncology · 2023Article
- Assessment of a novel biliary-specific near-infrared fluorescent dye (BL-760) for intraoperative detection of bile ducts and biliary leaks during hepatectomy in a preclinical swine model.Lasers in surgery and medicine · 2023Article
- Article
- Novel Personalized Score Predicts Risk for Postoperative Biliary Leak in Liver Surgery-a Retrospective Database Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Operative Time, Age, and Serum Albumin Predict Surgical Morbidity After Laparoscopic Liver Surgery.Surgical innovation · 2021Article
- Clinical impact of intraoperative bile leakage during laparoscopic liver resection.Surgical endoscopy · 2021Article
- Article
- Variation in Drain Management Among Patients Undergoing Major Hepatectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Letter to the Editor: Bile Leak Reduction with Laparoscopic Versus Open Liver Resection: A Multi-institutional Propensity Score-Adjusted Multivariable Regression Analysis.World journal of surgery · 2020Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess systematically the safety and efficacy of bile leakage test in liver resection.
methodsRandomized controlled trials and controlled clinical trials involving the bile leakage test were included in a systematic literature search. Two authors independently assessed the studies for inclusion and extracted the data. A meta-analysis was conducted to estimate postoperative bile leakage, intraoperative positive bile leakage, and complications. We used either the fixed-effects or random-effects model.
resultsEight studies involving a total of 1253 patients were included and they all involved the bile leakage test in liver resection. The bile leakage test group was associated with a significant reduction in bile leakage compared with the non-bile leakage test group (RR = 0.39, 95%CI: 0.23-0.67; I (2) = 3%). The white test had superiority for detection of intraoperative bile leakage compared with the saline solution test (RR = 2.38, 95%CI: 1.24-4.56, P = 0.009). No significant intergroup differences were observed in total number of complications, ileus, liver failure, intraperitoneal hemorrhage, pulmonary disorder, abdominal infection, and wound infection.
conclusionThe bile leakage test reduced postoperative bile leakage and did not increase incidence of complications. Fat emulsion is the best choice of solution for the test.
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