Evidence map›Paper›PMID 24363276›Full record

ArticleAmerican journal of hypertension2014

Alcohol consumption and ambulatory blood pressure: a community-based study in an elderly cohort.

Marie-Perrine Jaubert, Zhezhen Jin, Cesare Russo, Joseph E Schwartz, Shunichi Homma, Mitchell S V Elkind, Tatjana Rundek, Ralph L Sacco, Marco R Di Tullio

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Effect of alcohol on blood pressure.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Alcohol Use and Blood Pressure Among Older Couples: The Moderating Role of Negative Marital Quality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Alternate mechanisms and considerations for alcohol's effect on salt sensitivity.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Marie-Perrine JaubertDepartment of Medicine, Columbia University, New York, New York.
Zhezhen Jin
Cesare Russo
Joseph E Schwartz
Shunichi Homma
Mitchell S V Elkind
Tatjana Rundek
Ralph L Sacco
Marco R Di Tullio
Columbia University · USUniversity of Miami · USStony Brook University · US

Funding

Stroke Incidence and Risk Factors in a Tri-Ethnic RegionR37NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 2008 to 2014
$12.1M
ARCH PLAQUES AND STROKE IN AN ETHNICALLY MIXED COMMUNITYR01NS036286 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DI TULLIO, MARCO R · 1997 to 2009
$3.4M
NINDS NIH HHS R01 NS036286NINDS NIH HHS R01 NS36286NINDS NIH HHS R37 NS029993NINDS NIH HHS R37 NS29993
6 · The paper itself

Abstract

backgroundAlthough heavy alcohol consumption is associated with hypertension, the impact of lighter consumption on blood pressure (BP) is controversial. The protective effect of light alcohol consumption on cardiovascular disease described in previous studies could be, in part, mediated by effects of alcohol on BP. However, only a few studies investigating the association between alcohol and BP included elderly subjects, despite their higher risk of hypertension sequelae. Accordingly, we evaluated the relationship between alcohol consumption and 24-hour ambulatory BP in a community-based elderly cohort.

methodsAmong the participants in the Cardiac Abnormalities and Brain Lesion study, 553 subjects (mean age = 70.6 ± 9.6 years) who underwent 24-hour ambulatory BP monitoring were examined. Alcohol consumption was categorized as (i) none (reference; <1 drink/month); (ii) very light consumption (1 drink/month to 1 drink/week); (iii) light consumption (2 drinks/week to 1 drink/day); (iv) moderate-to-heavy consumption (>1 drink/day). Former drinkers were excluded.

resultsAfter adjustment for relevant covariables, mean values of daytime diastolic BP (DBP), nighttime DBP, and 24-hour DBP were significantly higher in moderate-to-heavy drinkers than in the reference group, whereas systolic BP parameters were not significantly different across consumption groups. Daytime systolic BP and DBP variability (SD of the measurements) were significantly lower in very light drinkers than in the reference group, independent of potential confounders.

conclusionsModerate-to-heavy alcohol consumption was associated with higher DBP values. Very light alcohol consumption was associated with reduced daytime BP variability. The latter association may contribute to the known beneficial cardiovascular effects of light alcohol consumption.

Indexed as

Blood PressureCircadian RhythmAgedAged, 80 and overAge FactorsAlcohol DrinkingBlood Pressure Monitoring, AmbulatoryCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedTime Factorsalcoholambulatory blood pressure monitoringblood pressureblood pressure variabilityhypertension.

Identifiers

PMID24363276
PMCPMC3978947
OpenAlexW2080354837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.