ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2014
Effect of GABAergic inhibition on odorant concentration coding in mushroom body intrinsic neurons of the honeybee.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Gain modulation and odor concentration invariance in early olfactory networks.PLoS computational biology · 2023Article
- In Search for the Retrievable Memory Trace in an Insect Brain.Frontiers in systems neuroscience · 2022Review
- Segregation of Unknown Odors From Mixtures Based on Stimulus Onset Asynchrony in Honey Bees.Frontiers in behavioral neuroscience · 2019Article
- In-situ recording of ionic currents in projection neurons and Kenyon cells in the olfactory pathway of the honeybee.PloS one · 2018Article
- Relationship between brain plasticity, learning and foraging performance in honey bees.PloS one · 2018Article
- Neural Organization of A3 Mushroom Body Extrinsic Neurons in the Honeybee Brain.Frontiers in neuroanatomy · 2018Article
- Fat Body Organ Culture System in Aedes Aegypti, a Vector of Zika Virus.Journal of visualized experiments : JoVE · 2017Article
- The Circuitry of Olfactory Projection Neurons in the Brain of the Honeybee,Frontiers in neuroanatomy · 2016Article
- It takes two-coincidence coding within the dual olfactory pathway of the honeybee.Frontiers in physiology · 2015Article
- GABAergic feedback signaling into the calyces of the mushroom bodies enables olfactory reversal learning in honey bees.Frontiers in behavioral neuroscience · 2015Article
- Honeybee Kenyon cells are regulated by a tonic GABA receptor conductance.Journal of neurophysiology · 2014Article
- Data-driven inference of network connectivity for modeling the dynamics of neural codes in the insect antennal lobe.Frontiers in computational neuroscience · 2014Article
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3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kenyon cells, the intrinsic neurons of the insect mushroom body, have the intriguing property of responding in a sparse way to odorants. Sparse neuronal codes are often invariant to changes in stimulus intensity and duration, and sparse coding often depends on global inhibition. We tested if this is the case for honeybees' Kenyon cells, too, and used in vivo Ca²⁺ imaging to record their responses to different odorant concentrations. Kenyon cells responded not only to the onset of odorant stimuli (ON responses), but also to their termination (OFF responses). Both, ON and OFF responses increased with increasing odorant concentration. ON responses were phasic and invariant to the duration of odorant stimuli, while OFF responses increased with increasing odorant duration. Pharmacological blocking of GABA receptors in the brain revealed that ionotropic GABA(A) and metabotropic GABA(B) receptors attenuate Kenyon cells' ON responses without changing their OFF responses. Ionotropic GABA(A) receptors attenuated Kenyon cell ON responses more strongly than metabotropic GABA(B) receptors. However, the response dynamic, temporal resolution and paired-pulse depression did not depend on GABA(A) transmission. These data are discussed in the context of mechanisms leading to sparse coding in Kenyon cells.
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