Evidence map›Paper›PMID 24362882›Full record

ArticleWorld journal of urology2014

Impact of preoperative immunonutrition on morbidity following cystectomy for bladder cancer: a case-control pilot study.

J Bertrand, N Siegler, T Murez, G Poinas, B Segui, D Ayuso, P Gres, L Wagner, R Thuret, P Costa and 1 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06002269 (A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06002269 nacompletednot on this mapstarted 2024, after this paper: background citation

A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients: the BOOST Study

TypeinterventionalSponsorUniversity of UtahRan2024 to 2025Enrolled8ConditionsBladder Cancer, Cystectomy, ChemotherapyArmsDietary and Exercise Intervention
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Preoperative immunonutrition and carbohydrate loading associated with improved bowel function after radical cystectomy.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

J BertrandDepartment of Uro-Andrology, Carémeau University Hospital, Nîmes, France, j_bertrand06@hotmail.com.
N Siegler
T Murez
G Poinas
B Segui
D Ayuso
P Gres
L Wagner
R Thuret
P Costa
S Droupy
Hôpital Lapeyronie · FRClinique Mutualiste de l'Estuaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare postoperative complications in patients with or without preoperative immunonutrition before cystectomy.

methodsA prospective, multicenter, pilot, case-control study was conducted during 6 months. Patients with 7-day preoperative immunonutrition were prospectively included and compared with a retrospective, matched control group without immunonutrition. Early complication rates and the length of hospital stay were analyzed. The bilateral type I error was <0.05; the power was 90%. Thirty patients in each group were required.

resultsThirty patients were included in each group, on a comparable basis. In the immunonutrition group, fewer postoperative complications (40 vs. 76.7%; p = 0.008), less paralytic ileus at D7 (6.6 vs. 33.3%; p = 0.02), fewer infections (23.3 vs. 60%; p = 0.008), and in particular less pyelonephritis (16.7 vs. 46.7%; p = 0.03) occurred. Clavien's grades for complications were higher in the control group (p = 0.04). Mortality, pulmonary embolism, anastomotic fistulae, and wound dehiscence were similar between two groups. The length of stay was reduced by 3 days in the immunonutrition group.

conclusionsIn this pilot case-control study, immunonutrition is associated with a decrease in postoperative complications, urinary tract infections, Clavien's grade for complications, and paralytic ileus in patients undergoing cystectomy for bladder cancer. Prospective randomized placebo control studies are needed to confirm these promising results.

Indexed as

ImmunotherapyNutrition TherapyPreoperative CareAgedAged, 80 and overCase-Control StudiesCystectomyFemaleHumansIncidenceMaleMiddle AgedPilot ProjectsPostoperative ComplicationsProspective StudiesPyelonephritis

Identifiers

PMID24362882
OpenAlexW2048988566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.