ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014
Glucocorticoid-induced diabetes mellitus in patients with lymphoma treated with CHOP chemotherapy.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 42 citations in OpenAlex.
- Associated Factors and Dose-Response of Steroid-Induced Diabetes Mellitus in Dermatology Inpatients: A Retrospective Study.Dermatology research and practice · 2026Article
- Risk of Type II Diabetes Mellitus Among B-Cell Non-Hodgkin's Lymphoma Survivors.Cancer medicine · 2026Article
- Risk of diabetes and the impact on preexisting diabetes in patients with lymphoma treated with steroid-containing immunochemotherapy.Blood advances · 2022Article
- High glucose: an emerging association between diabetes mellitus and cancer progression.Journal of molecular medicine (Berlin, Germany) · 2021Review
- Impact of prednisolone dosage in the CHOP regimen for follicular lymphoma: a retrospective study.International journal of hematology · 2020Article
- Adverse events associated with prophylactic corticosteroid use before extubation: a cohort study.Annals of translational medicine · 2020Article
- Patterns of Glucose Fluctuation are Challenging in Patients Treated for Non-Hodgkin's Lymphoma.International journal of general medicine · 2020Article
- Partners in Oncology Care: Coordinated Follicular Lymphoma Management.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2019Article
- Early incidence of glucocorticoid-induced diabetes in patients with brain tumors: a retrospective study of the first 7 days of treatment.Neuro-oncology practice · 2018Article
- Incidence of Diabetes After Cancer Development: A Korean National Cohort Study.JAMA oncology · 2018Article
- Impact of Anthracyclines on Diabetes Mellitus Development in B-Cell Lymphoma Patients: A Nationwide Population-based Study.Clinical drug investigation · 2018Article
- The influence on survival of glucocorticoid induced diabetes in cancer patients with metastatic spinal cord compression.Clinical and translational radiation oncology · 2018Article
- Glucocorticoid-induced diabetes in patients with metastatic spinal cord compression.Endocrine connections · 2018Article
- The Elevation of Cardio-Ankle Vascular Index in a Patient With Malignant Lymphoma Treated With a Combination Therapy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone.Journal of clinical medicine research · 2017Article
- Acute Hyperglycemia Associated with Anti-Cancer Medication.Endocrinology and metabolism (Seoul, Korea) · 2017Review
- From obesity to diabetes and cancer: epidemiological links and role of therapies.British journal of cancer · 2016Review
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeGlucocorticoid-induced diabetes mellitus (GDM) is a major complication arising from corticosteroid administration, but there is lack of studies on GDM attributing to CHOP chemotherapy. We studied the incidence and risk factors for GDM development in patients with lymphoma during CHOP chemotherapy.
methodsWe analyzed 80 patients with lymphoma treated with a CHOP regimen with or without rituximab between 2004 and 2012 at the University of Tsukuba hospital. Patients with a known history of DM were excluded. Diagnosis of DM was performed according to the American Diabetes Association's criteria.
resultsAmong the 80 patients, 26 (32.5 %) developed GDM. We found that age ≥ 60 years, glycated hemoglobin (HbA1c) levels >6.1 %, body mass index (BMI) >30 kg/m(2), prednisolone administration prior to chemotherapy, history of hypertension or hypertension at admission, and the presence of metabolic syndrome were significant (p ≤ 0.05) factors associated with GDM development by univariate analysis. Multivariate analysis revealed that age ≥ 60 years [p<0.05; hazard ratio (HR)=3.59; 95 % confidence interval (CI), 1.22-10.51], HbA1c levels >6.1 % (p<0.05; HR=9.35; 95%CI, 1.45-60.34), and BMI >30 kg/m(2) (p=0.052; HR=6.27; 95%CI, 0.98-40.00) were independently significant association factors.
conclusionThe results suggest a guideline for plasma glucose monitoring during CHOP chemotherapy in patients with no history of DM.
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