Evidence map›Paper›PMID 24362843›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014

Breast cancer survivors willingness to participate in an acupuncture clinical trial: a qualitative study.

Marilyn M Schapira, Elizabeth R Mackenzie, Regina Lam, David Casarett, Christina M Seluzicki, Frances K Barg, Jun J Mao

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04920097 (Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy), which is not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 6 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04920097 nacompletednot on this mapstarted 2021, after this paper: background citation

Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2021 to 2026Enrolled238ConditionsChemotherapy-induced NeuropathyArmsIn-person training for seed placement and APA, Virtual training for seed placement and APA, Usual Care, Post-training zoom session for seed placement and APA coaching
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  9. The effect of acupuncture on hot flashes and sleep disturbances in women with breast cancer receiving endocrine therapy: a pre-post quasi-interventional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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  18. A Wellness Program for Cancer Survivors and Caregivers: Developing an Integrative Pilot Program with Exercise, Nutrition, and Complementary Medicine.Journal of cancer education : the official journal of the American Association for Cancer Education · 2016
    Article
  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marilyn M SchapiraThe Philadelphia VA Center for Health Equity Research and Promotion, University of Pennsylvania, Philadelphia, PA, USA, mschap@upenn.edu.
Elizabeth R Mackenzie
Regina Lam
David Casarett
Christina M Seluzicki
Frances K Barg
Jun J Mao
University of Pennsylvania · US

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SHELLEY L BERGER · 1985 to 2026
$222.3M
Acupuncture and aromatase inhibitor ralated arthralgiaR21AT004695 · NCCIH · UNIVERSITY OF PENNSYLVANIA · PI MAO, JUN J · 2009 to 2011
$624k
NCCIH NIH HHS R21 AT004695NCI NIH HHS P30 CA016520
6 · The paper itself

Abstract

purposeAcupuncture is a complementary and alternative medicine (CAM) modality that shows promise as a component of supportive breast cancer care. Lack of robust recruitment for clinical trial entry has limited the evidence base for acupuncture as a treatment modality among breast cancer survivors. The objective of this study is to identify key decision-making factors among breast cancer survivors considering entry into an acupuncture clinical trial for treatment of symptoms.

methodsSemistructured interviews were conducted among African-American (n=12) and Caucasian (n=13) breast cancer survivors. Verbatim transcripts were made and analyzed by two or more independent coders using NVivo software. Major recurring themes were identified and a theoretical framework developed.

resultsSix themes emerged reflecting key attributes of the decision to enter a clinical trial: (1) symptom appraisal, (2) practical barriers (e.g., distance and travel), (3) beliefs about the interventions (e.g., fear of needles and dislike of medications), (4) comfort with elements of clinical trial design (e.g., randomization, the nature of the control intervention, and blinding), (5) trust, and (6) altruism. African-American and Caucasian women weighed similar attributes but differed in the information sources sought regarding clinical trial entry and in concerns regarding the use of a placebo in a clinical trial.

conclusionsOur findings contribute to the development of a theoretical model of decision making for breast cancer survivors considering participation in a CAM clinical trial. Insights regarding the decision making process can inform interventions to support informed decision making and robust recruitment to CAM trials among cancer survivors.

Indexed as

Acupuncture TherapyAdultAgedBlack or African AmericanBreast NeoplasmsDecision MakingFemaleHumansMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPatient Acceptance of Health CareSurvivorsWhite People

Identifiers

PMID24362843
PMCPMC4162629
OpenAlexW2141549622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.